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AB5848

Sigma-Aldrich

Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat

Chemicon®, from rabbit

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human, rat

Hersteller/Markenname

Chemicon®

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... GABBR2(9568)

Allgemeine Beschreibung

The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA(A) and GABA© receptors and GABA(B), the latter of which acts through a G protein mechanism. GABA(B)R2 is one of the two G-protein coupled receptors for GABA(B) that acts as a heteromeric assembly with GABA(B)R1.

Spezifität

GABAB Receptor R2 subunit, N-terminus. No reactivity with GABABR1 has been detected.

Immunogen

Epitope: a.a. 42-54 rat
peptide residues 42-54 of the rat 105 kDa GABA(b)R2 protein

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurotransmitter & Rezeptoren
Immunoblotting: 1:500-1:1,000. Membrane preparations with proteinase inhibitors are recommended. Whole rat brain membrane preparations. The antibody detects a ~105kDa band under standard western conditions. The immunogen used is 100% conserved in human by sequence analysis; other species have not been examined for reactivity or homology.

Optimal working dilutions must be determined by end user.
This Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat is validated for use in WB for the detection of GABA B Receptor R2.

Physikalische Form

Format: Purified
Purified immunoglobulin. Liquid. Buffer = PBS containing 0.02% sodium azide.

Lagerung und Haltbarkeit

Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

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Williams, JM; Guevremont, D; Mason-Parker, SE; Luxmanan, C; Tate, WP; Abraham, WC
The Journal of Neuroscience null
Distribution and function of GABAB receptors in spider peripheral mechanosensilla.
Panek, I; Meisner, S; Torkkeli, PH
Journal of Neurophysiology null
Immunohistochemical and immunoblot analysis of gamma-aminobutyric acid B receptor in the prefrontal cortex of subjects with schizophrenia and bipolar disorder.
Masanori Ishikawa, Katsuyoshi Mizukami, Masahiko Iwakiri, Takashi Asada
Neuroscience Letters null
Functional expression of the GABAB receptor in human airway smooth muscle.
Osawa, Y; Xu, D; Sternberg, D; Sonett, JR; D'Armiento, J; Panettieri, RA; Emala, CW
American Journal of Physiology. Lung Cellular and Molecular Physiology null

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