AB5340P
Anti-Cocaine and Amphetamine Related Transcript Antibody
Chemicon®, from chicken
Synonym(e):
CART/CARP
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
chicken
Qualitätsniveau
Antikörperform
affinity purified immunoglobulin
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Aufgereinigt durch
affinity chromatography
Speziesreaktivität
mouse, rat
Hersteller/Markenname
Chemicon®
Methode(n)
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
Isotyp
IgY
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
dry ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
mouse ... Cartpt(27220)
rat ... Cartpt(29131)
Verwandte Kategorien
Spezifität
Recognizes Cocaine and Amphetamine Related Transcript (CART). CART has been found to control satiety modulating the actions of two key regulators of food intake, leptin and NPY. Starvation decreases CART levels in the arcuate nucleus (Kristensen et al. 1998). Obese animals have virtually no CART. CART inhibits both normal and starvation-induced feeding, and completely inhibits NPY-induced feeding. Immunoneutralization of CART by administration of anti-CART resulted into higher food intake suggesting that CART is an endogenous regulator of food intake.
Immunogen
Mouse/rat CART peptide (55-102).
Anwendung
Research Category
Neurowissenschaft
Neurowissenschaft
Research Sub Category
ZNS-Kontrolle des Stoffwechsels
Belohnung & Sucht
ZNS-Kontrolle des Stoffwechsels
Belohnung & Sucht
Detect Cocaine & Amphetamine Related Transcript using this Anti-Cocaine & Amphetamine Related Transcript Antibody validated for use in ELISA, WB, IH.
Western blotting: 1-10 μg/mL using ECL.
Immunohistochemistry: It has been reported that the antibody will recognize CART in neurons (cell bodies) from the rat hypothalamic arcuate nucleus.
ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well.
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: It has been reported that the antibody will recognize CART in neurons (cell bodies) from the rat hypothalamic arcuate nucleus.
ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well.
Optimal working dilutions must be determined by the end user.
Physikalische Form
Affinity purified immunoglobulin. Liquid in PBS with 0.1% BSA
Lagerung und Haltbarkeit
Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Sonstige Hinweise
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Maria Collin et al.
Neuroreport, 13(7), 945-951 (2002-05-11)
Serotonin (5-hydroxytryptamine; 5-HT) is a regulator of feeding behavior. The effect of serotonin on food intake is believed to be primarily mediated via 5-HT(1A) and 5-HT(2C) receptors, which both are expressed in hypothalamic regions implicated in regulation of feeding behavior.
Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: focus on orexin targets involved in control of food and water intake.
Matilda Backberg, Guillaume Hervieu, Shelagh Wilson, Bjorn Meister
The European Journal of Neuroscience null
Plasma membrane and vesicular glutamate transporter mRNAs/proteins in hypothalamic neurons that regulate body weight.
Maria Collin, Matilda Backberg, Marie-Louise Ovesjo, Gilberto Fisone, Robert H Edwards et al.
The European Journal of Neuroscience null
M Bäckberg et al.
Journal of neuroendocrinology, 15(1), 1-14 (2003-01-22)
Gamma-aminobutyric acid (GABA) interacts with hypothalamic neuronal pathways regulating feeding behaviour. GABA has been reported to stimulate feeding via both ionotropic GABA(A) and metabotropic GABA(B) receptors. The functional form of the GABA(B) receptor is a heterodimer consisting of GABA(B) receptor-1
B Meister
Vitamins and hormones, 59, 265-304 (2000-03-14)
Food intake is regulated via neural circuits located in the hypothalamus. During the past decade our knowledge on the specific mediators and neuronal networks that regulate food intake and body weight has increased dramatically. An important contribution to the understanding
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
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