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Key Documents

AB5122

Sigma-Aldrich

Anti-Adrenergic Receptor Antibody, β 3

Chemicon®, from rabbit

Synonym(e):

Anti-Anti-B3AR, Anti-Anti-GPCR

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ADRB3(155)

Spezifität

Human beta 3 adrenergic receptor (B3AR) is a member of the G-protein coupled receptor superfamily. They typically contain 7 transmembrane domains (Barak et al., 1995) Human B3AR is 408 aa membrane protein (Emorine et al., 1989; Grannenman et al., 1992; Van Spronsen et al., 1993; Lelias et al., 1993).

Immunogen

A 19 aa sequence at the C-terminus of the human B3AR, splce variant 3 (Emorine et al., 1989; Grannenman et al., 1992; Van Spronsen et al., 1993; Lelias et al., 1993). Control peptide is available under catalog number AG388.

Anwendung

Anti-Adrenergic Receptor Antibody, β 3 detects level of Adrenergic Receptor & has been published & validated for use in ELISA, IH & WB.
Western blot: 1-10 μg/mL using Chemiluminescence technique

ELISA: 1:10,000 - 100,000

Immunohistochemistry: 2-20 μg in formaldehyde fixed tissue.

Optimal working dilutions must be determined by end user.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

J G Granneman et al.
Molecular pharmacology, 42(6), 964-970 (1992-12-01)
DNA blot analysis of the cloned rat beta 3-adrenergic receptor gene revealed unexpected restriction enzyme cleavage sites that suggested the presence of one or more introns near the end of the coding block. This region of the rat gene was
Stimulation of the ADRB3 adrenergic receptor induces relaxation of human placental arteries: influence of preeclampsia.
Rouget, C; Barthez, O; Goirand, F; Leroy, MJ; Breuiller-Fouche, M; Rakotoniaina et al.
Biology of reproduction null
{beta}1, {beta}2, {beta}3-Adrenoceptors and NHERF1 Expression in Human Bronchi and Their Modifications in Cystic Fibrosis.
Bossard F, Silantieff E, Lavazais-Blancou E, Robay A, Sagan C, Rozec B, Gauthier C
American Journal of Respiratory Cell and Molecular Biology null
J M Lelias et al.
FEBS letters, 324(2), 127-130 (1993-06-14)
We report the molecular cloning of a beta 3-adrenergic receptor [beta 3-AR] cDNA from human brown adipose tissue. The cDNA-encoded protein is identical to the previously cloned beta 3-AR but with 6 additional amino acids at the C-terminus. The C-terminus
The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor.
Barak, L S, et al.
Biochemistry, 34, 15407-15414 (1995)

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