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Key Documents

AB3349

Sigma-Aldrich

Anti-PRMT5 Antibody, CT

Chemicon®, from rabbit

Synonym(e):

Anti-HRMT1L5, Anti-HSL7, Anti-IBP72, Anti-JBP1, Anti-SKB1, Anti-SKB1Hs

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PRMT5(10419)

Spezifität

Reacts with PRMT5.

Immunogen

Epitope: C-terminus
Synthetic peptide from C-terminus of human PRMT5.

Anwendung

Research Category
Epigenetik & nukleäre Funktionen
Research Sub Category
Histone
Anti-PRMT5 Antibody, C-terminus is a high quality Rabbit Polyclonal Antibody for the detection of PRMT5 & has been validated in ELISA & WB.
Western Blot: 1:100-1:500. Reacts with a band of approximately 70 kDa on whole HL60 cell lysate. Additional bands may be present depending on sample used.

ELISA (direct): 1:1,000

Optimal working dilutions must be determined by the end user.

Verlinkung

Replaces: MABE551

Physikalische Form

Format: Purified
Purified immunoglobulin in PBS containing 0.09% sodium azide.

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Hinweis zur Analyse

Control
POSITIVE CONTROL: HL60 cell lysates.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Arginine methylation of a mitochondrial guide RNA binding protein from Trypanosoma brucei.
Pelletier, M, et al.
Molecular and Biochemical Parasitology, 118, 49-59 (2001)
Establishment of a versatile seminoma model indicates cellular plasticity of germ cell tumor cells.
Daniel Nettersheim,Birgit Westernstroer,Natalie Haas,Anke Leinhaas,Oliver Brustle et al.
Genes Chromosomes Cancer null
A Frankel et al.
The Journal of biological chemistry, 275(42), 32974-32982 (2000-08-10)
S-Adenosyl-l-methionine-dependent protein arginine N-methyltransferases (PRMTs) catalyze the methylation of arginine residues within a variety of proteins. At least four distinct mammalian family members have now been described, including PRMT1, PRMT3, CARM1/PRMT4, and JBP1/PRMT5. To more fully define the physiological role
L L Belyanskaya et al.
The Journal of biological chemistry, 276(22), 18681-18687 (2001-03-30)
In contrast to the knowledge regarding the function of chimeric Ewing sarcoma (EWS) fusion proteins that arise from chromosomal translocation, the cellular function of the RNA binding EWS protein is poorly characterized. EWS protein had been found mainly in the
X Zhang et al.
The EMBO journal, 19(14), 3509-3519 (2000-07-19)
Protein arginine methylation has been implicated in signal transduction, nuclear transport and transcription regulation. Protein arginine methyltransferases (PRMTs) mediate the AdoMet-dependent methylation of many proteins, including many RNA binding proteins involved in various aspects of RNA processing and/or transport. Here

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