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Key Documents

AB2233

Sigma-Aldrich

Anti-Galanin Antibody

serum, from rabbit

Synonym(e):

galanin prepropeptide, galanin-message-associated peptide, galanin-related peptide

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

rat

Speziesreaktivität (Voraussage durch Homologie)

mouse, boar, human

Methode(n)

immunohistochemistry: suitable (paraffin)

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... GAL(51083)

Allgemeine Beschreibung

Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer′s disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.

Spezifität

Cat. # AB2233 recognizes Galanin
Reactivity with other species has not been determined.

Immunogen

Synthetic Linear Peptide

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurochemie & Neurotrophine
Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).

Qualität

Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.

Zielbeschreibung

13.3 kDa

Physikalische Form

Serum with 0.05% NaN3

Lagerung und Haltbarkeit

Maintain at -20°C for up to 1 year from date of receipt.

Hinweis zur Analyse

Control
Rat Cerebellum Tissue

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Yutaro Komuro et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(42), 8725-8741 (2021-09-01)
Galanin, one of the most inducible neuropeptides, is widely present in developing brains, and its expression is altered by pathologic events (e.g., epilepsy, ischemia, and axotomy). The roles of galanin in brain development under both normal and pathologic conditions have
Katarzyna Palus et al.
Journal of chemical neuroanatomy, 72, 25-33 (2016-01-06)
The purpose of the present study was to determine the response of the porcine coeliac-superior mesenteric ganglion complex (CSMG) neurons projecting to the prepyloric area of the porcine stomach to peripheral neuronal damage following partial stomach resection. To identify the
Joanna L Elson et al.
Neurotoxicity research, 34(1), 16-31 (2017-12-09)
Parkinson's disease (PD) is conventionally seen as resulting from single-system neurodegeneration affecting nigrostriatal dopaminergic neurons. However, accumulating evidence indicates multi-system degeneration and neurotransmitter deficiencies, including cholinergic neurons which degenerate in a brainstem nucleus, the pedunculopontine nucleus (PPN), resulting in motor
Katarzyna Palus et al.
PloS one, 10(11), e0143661-e0143661 (2015-11-26)
This experiment was designed to establish the localization and neurochemical phenotyping of sympathetic neurons supplying prepyloric area of the porcine stomach in a physiological state and during acetylsalicylic acid (ASA) induced gastritis. In order to localize the sympathetic perikarya the
Marta Gańko et al.
Journal of molecular neuroscience : MN, 54(2), 188-198 (2014-03-20)
The main goal of our research was to study the possible alterations of the chemical coding of the dorsal motor vagal nucleus (DMX) neurons projecting to the porcine stomach prepyloric region following prolonged acetylsalicylic acid supplementation. Fast Blue (FB) was

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