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AB16661

Sigma-Aldrich

Anti-PARP Poly ADP-ribose Polymerase-1 Antibody

serum, Chemicon®

Synonym(e):

Poly [ADP-ribose] polymerase 1, PARP-1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] synthase 1, ARTD1

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

rat, human, bovine, mouse

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

NM_001618.3

UniProt-Hinterlegungsnummer

P09874

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

bovine ... Parp1(286764)
human ... PARP1(142)
mouse ... Parp1(11545)
rat ... Parp1(25591)

Spezifität

Recognizes 116 kDa PARP-1 and the 85 kDa apoptosis-related cleavage fragment.

Immunogen

Synthetic peptide based on the sequence from the C-terminal portion of the bovine PARP automodification domain (amino acids 509-524) conjugated to a carrier.

Anwendung

Research Category
Apoptose & Krebs

Stoffwechsel
Research Sub Category
Apoptose - Weiterführende Produkte

Enzyme & Biochemie
This Anti-PARP Poly ADP-ribose Polymerase-1 Antibody is validated for use in ELISA, WB for the detection of PARP Poly ADP-ribose Polymerase-1.
Western blot: 1:500 using alkaline phosphatase.

ELISA

Optimal working dilutions must be determined by end user.

Verlinkung

Replaces: 04-575; 04-576

Physikalische Form

Antiserum containing 0.05% sodium azide. Liquid containing 0.05% sodium azide.

Lagerung und Haltbarkeit

Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Y A Lazebnik et al.
Nature, 371(6495), 346-347 (1994-09-22)
Recent studies suggest that proteases of the interleukin 1-beta-converting enzyme (ICE)/ced-3 family are involved in initiating the active phase of apoptosis. Here we identify a novel protease resembling ICE (prICE) that is active in a cell-free system that reproduces the
D Lamarre et al.
Biochimica et biophysica acta, 950(2), 147-160 (1988-07-13)
Poly(ADP ribose) polymerase (EC 2.4.2.30) was studied using monoclonal antibodies for three different epitopes on the enzyme. The epitopes were mapped in relation to the functional domains of the protein and the inhibitory properties of the antibodies. The intranuclear and
Lauren K Jillson et al.
Molecular cancer research : MCR, 19(7), 1123-1136 (2021-04-14)
Prostate cancer genomic subtypes that stratify aggressive disease and inform treatment decisions at the primary stage are currently limited. Previously, we functionally validated an aggressive subtype present in 15% of prostate cancer characterized by dual deletion of MAP3K7 and CHD1.
MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells.
Brest, P; Lassalle, S; Hofman, V; Bordone, O; Gavric Tanga, V; Bonnetaud, C; Moreilhon et al.
Endocrine-Related Cancer null
Hypermethylated in cancer 1 (HIC1), a tumor suppressor gene epigenetically deregulated in hyperparathyroid tumors by histone H3 lysine modification.
Svedlund, J; Koskinen Edblom, S; Marquez, VE; ?kerstrom, G; Bjorklund, P; Westin, G
The Journal of clinical endocrinology and metabolism null
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