8.51021

N₃-(PEG)₇-COOH (33 atoms)

Novabiochem^®

• Synonym(e): O-(2-Azidoethyl)-O′-(N-diglycolyl-2-aminoethyl)-heptaethyleneglycol
• Empirische Formel (Hill-System): C₂₂H₄₂N₄O₁₂
• CAS-Nummer: 846549-37-9
• Molekulargewicht: 554.59
• MDL-Nummer: MFCD10001327
• UNSPSC-Code: 12352106
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 400
• Produktlinie: Novabiochem^®
• Assay: ≥97.0% (HPLC)
• Form: oil
• Eignung der Reaktion: reaction type: click chemistry
• Hersteller/Markenname: Novabiochem^®
• Anwendung(en): peptide synthesis
• Lagertemp.: 2-8°C
• InChI: 1S/C22H42N4O12/c23-26-25-2-4-31-6-8-33-10-12-35-14-16-37-18-17-36-15-13-34-11-9-32-7-5-30-3-1-24-21(27)19-38-20-22(28)29/h1-20H2,(H,24,27)(H,28,29)
• InChIKey: WWDNBBVPYDZICO-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

This building block is prepared from highly purified PEG to ensure homogeneous products free from contaminating PEG oligomers. In this derivative the azido group acts as an orthogonally masked amine; it is stable to both TFA and piperidine but is easily converted to an amine by treatment with phosphines or thiols. For a similar spacer, see reference ^[1]. This material is now only available as an oil.

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references
^[1] J. Mack, et al. (1999) J. Peptide Sci., 6, 135.

Verlinkung

Replaces: 01-63-0103

Hinweis zur Analyse

Farbe (visuell): schwach gelb bis gelb
Aussehen der Substanz (visuell): Öl
Gehalt (HPLC, Fl.%): ≥ 97.0 % (a/a)

Rechtliche Hinweise

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315 - H319 - H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable