648480

Troponin I, Human Heart

• Synonym(e): Troponin I, Human Heart, hcTnI
• CAS-Nummer: 77108-40-8
• MDL-Nummer: MFCD00213059
• UNSPSC-Code: 12352202
• NACRES: NA.32

Eigenschaften

• Assay: ≥95% (SDS-PAGE)
• Qualitätsniveau: 100
• Form: lyophilized
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Löslichkeit: urea/Tris buffer (0.02 M Tris, HCl, pH 7.5, 7 M urea, 5 mM EDTA, 15 mM 2-mercaptoethanol): 1 mg/mL
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca²⁺, thus inhibiting the ATPase activity of actomyosin. Presence of Tnl in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for anti-sera production. Also useful as a tracer for iodination.

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca²⁺, thus inhibiting the ATPase activity of actomyosin. Presence of hcTnI in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for antisera production. Also useful as a tracer for iodination.

Warnhinweis

Toxicity: Standard Handling (A)

Physikalische Form

Lyophilized from 10 mM HCl.

Angaben zur Herstellung

Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Sonstige Hinweise

Falahati, A., et al. 1999. Am. Heart J. 137, 332.
Mangano, D.T. 1994. Anesthesiology 81, 1317.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany