5.05818

Scopolamine Hydrobromide

• Synonym(e): Scopolamine Hydrobromide, Muscarinic Acetylcholine Receptor (mAChR) Antagonist, Scopolamine, Levo-duboisine, Hyoscine, Scopoderm
• Empirische Formel (Hill-System): C₁₇H₂₁NO₄ · xHBr
• CAS-Nummer: 114-49-8
• Molekulargewicht: 303.35 (free base basis)
• UNSPSC-Code: 12352116
• NACRES: NA.77

Eigenschaften

• Assay: ≥99% (HPLC)
• Qualitätsniveau: 100
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: off-white
• Löslichkeit: H₂O: 100 mM
• Lagertemp.: 2-8°C
• InChI: 1S/C17H21NO4.Br/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10;/h2-6,11-16,19H,7-9H2,1H3;/t11?,12-,13+,14+,15-,16+;/m1./s1
• InChIKey: XUZPYCBMTSSDHK-AKTDCHNFSA-N

Beschreibung

Allgemeine Beschreibung

A competitive, non-selective antagonist for muscarinic acetylcholine receptors (mAChR). Most effective at treating motion sickness. It is also a research tool for inducing memory impairment in vivo. Frequently used in researches related to learning, memory and Alzheimer′s dementia.

Warnhinweis

Toxicity: Harmful (C)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Sonstige Hinweise

Klinkenberg, I., et al. 2010. Neurosci Biobehav Rev34, 1307.
Aparkes. W. 1995. Psychopharmacologia.7, 1.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H300 + H310 + H330
• P-Sätze: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Gefahreneinstufungen: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral
• Lagerklassenschlüssel: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3