5.05024

Ibotenic Acid

• Synonym(e): Ibotenic Acid, 2-amino-2-(3-hydroxyisoxazol-5-yl) acetic acid, α-Amino-(3-hydroxy-5-isoxazolyl)acet­ic acid, Glutamate Receptor Agonist, Ibotenic acid
• Empirische Formel (Hill-System): C₅H₆N₂O₄
• CAS-Nummer: 2552-55-8
• Molekulargewicht: 158.11
• MDL-Nummer: MFCD00069294
• UNSPSC-Code: 12352106
• NACRES: NA.77

Eigenschaften

• Assay: ≥99% (HPLC)
• Qualitätsniveau: 100
• Form: solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: white
• Löslichkeit: water: 10 mM
• Lagertemp.: −20°C
• InChI: 1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)
• InChIKey: IRJCBFDCFXCWGO-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

A highly potent agonist of NMDA and mGlu receptors. A frequently used brain-lesioning agent inducing excitotoxic lesions of neurons without damaging crossing fiber tracts.

Warnhinweis

Toxicity: Regulatory Review (Z)

Sonstige Hinweise

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Izquierdo, A., et al. 2013. J. Neurosci.33, 4105.
Rhodes, V., et al. 2013. J. Neurosci.33, 3380.
Yu, X., et al. 2012. Pharmacol. Biochem. & Beh.101, 479.
Albasser, M., et al. 2012. Beh. Neurosci.126, 659.
Eijkenboom, M., et al. 2000. Neurosci.101, 27.
Isacson, O., et al. 1984. Nature.311, 458.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P264 - P270 - P301 + P310 - P405 - P501
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable