14-448-M

Cdk2/Cyclin A Protein, active, 10 µg

Active, C-terminal His6-tagged human full length Cdk2 & N-terminal GST-tagged human full length Cyclin A, for use in Kinase Assays.

• UNSPSC-Code: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: human
• Qualitätsniveau: 100
• Rekombinant: expressed in baculovirus infected Sf21 cells
• Produktlinie: Upstate^®
• Spezifische Aktivität: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• Mol-Gew.: M_w 35 kDa
• Aufgereinigt durch: (The cdk2 is purified by Ni2+/NTA agarose and then activated using CAK and repurified by Q Sepharose and Ni2+/NTA agarose. The cyclin A is purified using glutathioneagarose)
• Speziesreaktivität: human
• Hersteller/Markenname: Upstate^®
• Methode(n): activity assay: suitable (kinase)
• Hinterlegungsnummer: (FUNCTION: SwissProt: P24941 # Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2. ); NM_001798.2
• NCBI-Hinterlegungsnummer: NM_001798.2; NM_052827.1
• UniProt-Hinterlegungsnummer: P24941

Beschreibung

Allgemeine Beschreibung

C-terminal His6-tagged human full length cdk2, and N-terminal GST-tagged human full length cyclin A

Biochem./physiol. Wirkung

Protein Target: CDK2/cyclinA

Target Sub-Family: CMGC

Verpackung

Also available in 10 μg size and in bulk

Also available in 250μg size, please inquire for pricing and availability.

Qualität

routinely evaluated by phosphorylation of Histone H1

Zielbeschreibung

CDK2/cyclinA

Verlinkung

Replaces: 14-407

Physikalische Form

The cdk2 is purified by Ni2+/NTA agarose and then activated using CAK and repurified by Q Sepharose^™ and Ni2+/NTA agarose. The cyclin A is purified using glutathioneagarose

Lagerung und Haltbarkeit

6 months at -70°C

Sonstige Hinweise

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Rechtliche Hinweise

Sepharose is a trademark of Cytiva

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°C): Not applicable