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Merck
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Key Documents

14-198

Sigma-Aldrich

MAP Kinase 2/Erk2 Protein, inactive, Mouse, 50 g

Unactive, recombinant full-length mouse p42 MAP Kinase 2/Erk2 fused with GST at the N terminus, for use in Kinase Assays.

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About This Item

UNSPSC-Code:
12352202
eCl@ss:
32160405
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Rekombinant

expressed in E. coli

Mol-Gew.

Mw 67.8 kDa

Hersteller/Markenname

Upstate®

Methode(n)

activity assay: suitable (kinase)

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Allgemeine Beschreibung

Product Source: expressed in E coli
Recombinant full-length mouse p42 MAP Kinase 2/Erk2 fused with GST at the N terminus

Qualität

routinely evaluated by phosphorylation of MBP (Catalog # 13-104) substrate in vitro.

Sonstige Hinweise

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Skin Sens. 1

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2


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Tian-Rui Xu et al.
The Biochemical journal, 413(1), 51-60 (2008-04-26)
FRET (fluorescence resonance energy transfer) and co-immunoprecipitation studies confirmed the capacity of beta-arrestin 2 to self-associate. Amino acids potentially involved in direct protein-protein interaction were identified via combinations of spot-immobilized peptide arrays and mapping of surface exposure. Among potential key
Maofu Fu et al.
Methods in molecular biology (Clifton, N.J.), 284, 15-36 (2004-06-03)
Signal transduction pathways mediate cell-cell interactions and integrate signals from the extracellular environment through specific receptors at the cell membrane. They play a pivotal role in regulating cellular growth and differentiation and in mediating many physiological and pathological processes, such
D Aronson et al.
The Journal of biological chemistry, 272(41), 25636-25640 (1997-11-05)
Contractile activity plays a critical role in the regulation of gene transcription in skeletal muscle, which in turn determines muscle functional capabilities. However, little is known about the molecular signaling mechanisms that convert contractile activity into gene regulatory responses in
O Zugasti et al.
Molecular and cellular biology, 21(19), 6706-6717 (2001-09-05)
Signals from the extracellular matrix are essential for the survival of many cell types. Dominant-negative mutants of two members of Rho family GTPases, Rac1 and Cdc42, mimic the loss of anchorage in primary mouse fibroblasts and are potent inducers of
Shawna D Persaud et al.
Cellular signalling, 25(1), 19-25 (2012-09-18)
All-trans retinoic acid (atRA), one of the active ingredients of vitamin A, exerts canonical activities to regulate gene expression mediated by nuclear RA receptors (RARs). AtRA could also elicit certain non-canonical activities including, mostly, rapid activation of extracellular signal regulated

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