1.37136

Tetrahydrofuran

EMPROVE^® ESSENTIAL

• Synonym(e): Butylenoxid, Oxolan, Tetramethylenoxid
• Empirische Formel (Hill-System): C₄H₈O
• CAS-Nummer: 109-99-9
• Molekulargewicht: 72.11
• Beilstein: 102391
• MDL-Nummer: MFCD00005356
• UNSPSC-Code: 12352005

Eigenschaften

• Dampfdichte: 2.5 (vs air)
• Qualitätsniveau: 500
• Dampfdruck: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• Produktlinie: EMPROVE^® ESSENTIAL
• Assay: ≥99.8% (GC)
• Form: liquid
• Selbstzündungstemp.: 610 °F
• Expl.-Gr.: 1.8-11.8 %
• Methode(n): API processing | polymorph screening: suitable
• Brechungsindex: n20/D 1.407 (lit.)
• pH-Wert: 7-8 (20 °C, 200 g/L in H₂O)
• bp: 65-67 °C (lit.)
• mp (Schmelzpunkt): −108 °C (lit.)
• Dichte: 0.889 g/mL at 25 °C (lit.)
• Anwendung(en): pharmaceutical
• Lagertemp.: 2-25°C
• SMILES String: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChIKey: WYURNTSHIVDZCO-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Anwendung

Tetrahydrofuran is a versatile organic solvent for API synthesis, as a pre-cursor to polymers and it is used for several extended applications during drug manufacturing. The performance of the processes increases with the usage of Tetrahydrofuran in certain API′s than other available solvents. Tetrahydrofuran Emprove^® Essential is manufactured according to GMP guidelines and is suitable for pharmaceutical applications.

Verlinkung

Emprove Documentation

Rechtliche Hinweise

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS07,GHS08
• Signalwort: Danger
• H-Sätze: H225 - H302 - H319 - H335 - H336 - H351
• P-Sätze: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2
• Zusätzliche Gefahrenhinweise: EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): -6.2 °F - closed cup
• Flammpunkt (°C): -21.2 °C - closed cup