1.04967

Kaliumcyanid

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

• Synonym(e): Kaliumcyanid, Cyanogenkalium
• Empirische Formel (Hill-System): CKN
• CAS-Nummer: 151-50-8
• Molekulargewicht: 65.12
• MDL-Nummer: MFCD00011397
• UNSPSC-Code: 12352302
• EG-Index-Nummer: 205-792-3
• NACRES: NA.21

Eigenschaften

• Qualität: ACS reagent
• Qualitätsniveau: 300
• Agentur: reag. ISO; reag. Ph. Eur.
• Produktlinie: EMSURE^®
• Assay: ≥97% (silver nitrate titration)
• Form: solid
• Wirksamkeit: 7.49 mg/kg LD₅₀, oral (Rat); 14.29 mg/kg LD₅₀, skin (Rabbit)
• pH-Wert: 11-12 (20 °C, 20 g/L in H₂O)
• bp: 1625 °C/1013 hPa
• mp (Schmelzpunkt): 634 °C
• Dichte: 1.55 g/cm³ at 20 °C
• Schüttdichte: 750 kg/m³
• Anionenspuren: chloride (Cl^-): ≤0.02%; phosphate (PO₄^3-): ≤0.005%; sulfate (SO₄^2-): ≤0.01%; sulfide (S^2-): ≤0.0005%; thiocyanate (SCN^-): ≤0.01%
• Kationenspuren: Fe: ≤0.01%; Na: ≤0.5%; Pb: ≤0.0002%
• Lagertemp.: no temp limit
• InChI: 1S/CN.K/c1-2;/q-1;+1
• InChIKey: NNFCIKHAZHQZJG-UHFFFAOYSA-N

Beschreibung

Anwendung

• Identification of Iminium Intermediates Generation in the Metabolism of Tepotinib Using LC-MS/MS: In Silico and Practical Approaches to Bioactivation Pathway Elucidation.: The research identifies iminium intermediates in the metabolism of tepotinib using liquid chromatography-mass spectrometry. Potassium cyanide is utilized to trap reactive intermediates, providing insights into drug metabolism pathways (Abdelhameed et al., 2020).


• Synthesis of stable-isotope-labeled N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide and N-(3-dimethylaminopropyl)-N′-ethylurea.: This paper describes the synthesis of stable-isotope-labeled compounds using potassium cyanide in the synthesis process to understand the chemical structure and reactivity of these labeled compounds (Cao et al., 2020).


• Carbon-13 synthesis and NMR spectroscopic geometric isomer evaluation to support the filing of teriflunomide.: The study involves the synthesis of carbon-13 labeled teriflunomide and its isomers, using potassium cyanide in the synthetic pathway. The NMR spectroscopic analysis helped in the evaluation of geometric isomers (Kurz et al., 2021).


• A hybrid lipid membrane coating "shape-locks" silver nanoparticles to prevent surface oxidation and silver ion dissolution.: This research develops a hybrid lipid membrane to stabilize silver nanoparticles, using potassium cyanide in the analytical phase to measure the prevention of silver ion dissolution and oxidation (Miesen et al., 2020).

Verlinkung

Ersetzt: PX1435; PX1435-5; PX1435-1; PX1435-20

Hinweis zur Analyse

Gehalt (argentometrisch): ≥ 97,0 %
Chlorid (Cl): ≤ 0,02 %
Phosphat (PO₄): ≤ 0,005 %
Sulfat (SO₄): ≤ 0,01 %
Sulfid (S): ≤ 0,0005 %
Thiocyanat (SCN): ≤ 0,01 %
Fe (Eisen): ≤ 0,01 %
Na (Natrium): ≤ 0,5 %
Pb (Blei): ≤ 0,0002 %
Entspricht ACS, Reag. Ph Eur

Rechtliche Hinweise

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS05,GHS09
• Signalwort: Danger
• H-Sätze: H290,H300 + H310 + H330,H372,H410
• P-Sätze: P262 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314
• Gefahreneinstufungen: Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1
• Zielorgane: Thyroid
• Zusätzliche Gefahrenhinweise: EUH032
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable