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Key Documents

09-143

Sigma-Aldrich

Anti-Brk Antibody

Upstate®, from rabbit

Synonym(e):

PTK6, protein tyrosine kinase 6, breast tumor kinase, protein-tyrosine kinase BRK

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

human

Hersteller/Markenname

Upstate®

Methode(n)

western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_005975.2

UniProt-Hinterlegungsnummer

Q13882

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PTK6(5753)

Spezifität

Recognizes Brk (breast tumor kinase, PTK6) at approximately 52 kDa. It can also recognize the 73 kDa ELF-related protein that shares 70% homology with the immunizing peptide.

Immunogen

KLH conjugated synthetic peptide corresponding to the N-terminal region of human Brk.

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
Cytoskelettale Signalübertragung
Detect Brk using this Anti-Brk Antibody validated for use in WB.

Qualität

Routinely evaluated by immunoblot.

Zielbeschreibung

52 kDa

Physikalische Form

ImmunoAffinity Purified
50 µg of affinity purified rabbit polyclonal IgG in 0.02 M PBS, 250 mM sodium chloride containing 0.1% sodium azide.

Lagerung und Haltbarkeit

Store for 1 year at 2-8°C from date of shipment.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Growth response of Escherichia coli ATCC 35218 adapted to several concentrations of sodium benzoate and potassium sorbate.
Santiesteban-Lopez NA, Rosales M, Palou E, Lopez-Malo A
Journal of Food Protection null
Andrea Haegebarth et al.
Cell cycle (Georgetown, Tex.), 4(9), 1239-1246 (2005-08-06)
The intracellular tyrosine kinase Brk is expressed in regenerating epithelial tissues with highest levels in the gastrointestinal tract and skin. In these tissues, Brk is restricted to epithelial cells that are exiting the cell cycle and undergoing terminal differentiation. While
Haoqun Qiu et al.
The Journal of biological chemistry, 277(37), 34634-34641 (2002-07-18)
Brk (breast tumor kinase) is a nonreceptor tyrosine kinase that is most closely related to the Frk family of kinases, and more distantly to Src family kinases. Brk was originally identified in a screen for tyrosine kinases that are overexpressed
Monika Kasprzycka et al.
The American journal of pathology, 168(5), 1631-1641 (2006-05-03)
Tyrosine kinases play a fundamental role in cell proliferation, survival, adhesion, and motility and have also been shown to mediate malignant cell transformation. Here we describe constitutive expression of the protein tyrosine kinase Brk in a large proportion of cutaneous
Haoqun Qiu et al.
Oncogene, 24(36), 5656-5664 (2005-05-05)
Breast tumor kinase (Brk) is a member of the Frk family of nonreceptor tyrosine kinases that is overexpressed in a high percentage of human breast tumors. The downstream substrates and effectors of Brk remain largely unidentified. In this study, we

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