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Merck
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Wichtige Dokumente

07-464

Sigma-Aldrich

Anti-Vav3 Antibody, human

Upstate®, from rabbit

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human

Hersteller/Markenname

Upstate®

Methode(n)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_006113

UniProt-Hinterlegungsnummer

Q9UKW4

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... VAV3(10451)

Spezifität

Vav3

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 566-591of human Vav3.

Anwendung

Research Category
Zelluläre Signaltransduktion
Research Sub Category
Cytoskelettale Signalübertragung
Anti-Vav3 Antibody, human detects level of Vav3 & has been published & validated for use in IP, WB, IC, IH.

Qualität

routinely evaluated by immunoblot in RIPA lysates from HeLa and Jurkat cells

Zielbeschreibung

98 kDa

Physikalische Form

Protein A purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl,0.05% sodium azide before the addition of glycerol to 30%
Format: Purified

Lagerung und Haltbarkeit

2 years at -20°C

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

VAV proteins as signal integrators for multi-subunit immune-recognition receptors.
Turner, Martin and Billadeau, Daniel D
Nature Reviews: Immunology, 2, 476-486 (2002)
Youjia Cao et al.
The EMBO journal, 21(18), 4809-4819 (2002-09-18)
The Rac/Rho-specific guanine nucleotide exchange factor, Vav-1, is a key component of the T-cell antigen receptor (TCR)-linked signaling machinery. Here we have used somatic cell gene-targeting technology to generate a Vav-1-deficient Jurkat T-cell line. The J.Vav1 cell line exhibits dramatic
Mapping cell-matrix stresses during stretch reveals inelastic reorganization of the cytoskeleton.
Nuria Gavara,Pere Roca-Cusachs,Raimon Sunyer,Ramon Farre,Daniel Navajas
Biophysical Journal null
Emanuela Dylgjeri et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(18), 5623-5637 (2019-07-04)
DNA-dependent protein kinase catalytic subunit (DNA-PK) is a pleiotropic kinase involved in DNA repair and transcriptional regulation. DNA-PK is deregulated in selected cancer types and is strongly associated with poor outcome. The underlying mechanisms by which DNA-PK promotes aggressive tumor
Mehdi Badaoui et al.
Cell reports, 32(1), 107842-107842 (2020-07-09)
Pseudomonas aeruginosa (Pa) represents the leading cause of airway infection in cystic fibrosis (CF). Early airways colonization can be explained by enhanced adhesion of Pa to the respiratory epithelium. RNA sequencing (RNA-seq) on fully differentiated primary cultures of airway epithelial
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