A-084

Androsten-3,17-dion-2,3,4-¹³C₃ -Lösung

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Synonym(e): Androsten-3,17-dion-2,3,4-¹³C₃ -Lösung
• Empirische Formel (Hill-System): ¹³C₃C₁₆H₂₆O₂
• CAS-Nummer: 327048-86-2
• Molekulargewicht: 289.39
• EG-Nummer: 200-835-2
• MDL-Nummer: MFCD17677359
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329770636
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material
• Form: liquid
• Leistungsmerkmale: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• Verpackung: ampule of 1 mL
• Hersteller/Markenname: Cerilliant^®
• Konzentration: 100 μg/mL in acetonitrile
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Anwendung(en): clinical testing
• Format: single component solution
• Lagertemp.: −20°C
• SMILES String: C[C@]12CC[C@H]3[C@@H](CCC4=[13CH][13C](=O)[13CH2]C[C@]34C)[C@@H]1CCC2=O
• InChI: 1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1/i7+1,11+1,13+1
• InChIKey: AEMFNILZOJDQLW-FZIFMXJCSA-N

Beschreibung

Allgemeine Beschreibung

Androstendion ist ein Hormon und Zwischenprodukt des biochemischen Signalwegs zum Erzeugen von Testosteron, Estron und Estradiol. Dieser stabil markierte interne Standard eignet sich für zahlreiche LC/MS- und GC/MS-Anwendungen in der Endokrinologie, klinischen Chemie, Neugeborenen-Screenings, Tests im Sport und Isotopenverdünnungsverfahren.

Anwendung

• Stable Isotope-Labeled Steroids: Research in "Biotechnol J" explores the production and purity of 9-OH-AD from phytosterols by balancing metabolic flux, utilizing stable isotope-labeled intermediates like Androstene-3,17-dione-¹³C₃ to elucidate the pathways involved in steroid metabolism (Zhu et al., 2024).


• Steroid Metabolism Studies: The work published in "Methods Mol Biol" details the scale-up of phytosterols bioconversion into Androstenedione, demonstrating the practical applications of carbon-13 enriched androstenedione in enhancing biochemical production processes and pharmaceutical research (Martínez-Cámara et al., 2023).


• Mass Spectrometry Standards: Another study in "Methods Mol Biol" discusses the biocatalysis of steroids in both aqueous and organic media, highlighting the use of carbon-13 tracers like Androstene-3,17-dione-¹³C₃ to track enzymatic reactions and optimize conditions for industrial applications (de Carvalho CCCR and Fernandes, 2023).


• Analytical Reference Material: Further use of Androstene-3,17-dione-¹³C₃ is reported in the small-scale bioconversion of β-Sitosterol, where microtiter plates and microfluidic reactors are employed to study steroid transformations, thus providing crucial insights for pharmaceutical and biochemical research (Marques et al., 2023).


• Pharmaceutical Research Chemicals: The identification and characterization of bile acid aerobic catabolic pathways using Pseudomonas highlight the utility of carbon-13 labeled compounds like Androstene-3,17-dione-¹³C₃ in understanding complex metabolic networks, aiding in the development of therapeutic agents (Luengo et al., 2023).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H302 + H312 + H332,H319
• P-Sätze: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 35.6 °F - closed cup
• Flammpunkt (°C): 2 °C - closed cup