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LM2212

Avanti

C12 Ceramide

Avanti Research™ - A Croda Brand LM2212, ethanol solution

Synonym(e):

N-(dodecanoyl)-sphing-4-enine

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About This Item

Empirische Formel (Hill-System):
C30H59NO3
CAS-Nummer:
74713-60-3
Molekulargewicht:
481.79
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

ethanol solution

Verpackung

pkg of 1 × 1 mL (LM2212-1EA)

Hersteller/Markenname

Avanti Research™ - A Croda Brand LM2212

Konzentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

Anwendung(en)

lipidomics
metabolomics

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

OC[C@]([H])(NC(CCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C30H59NO3/c1-3-5-7-9-11-13-14-15-16-18-19-21-23-25-29(33)28(27-32)31-30(34)26-24-22-20-17-12-10-8-6-4-2/h23,25,28-29,32-33H,3-22,24,26-27H2,1-2H3,(H,31,34)/b25-23+/t28-,29+/m0/s1

InChIKey

HXFPPRPLRSPNIB-VARSQMIESA-N

Allgemeine Beschreibung

Ceramide is a sphingolipid with long acyl chain attached to a fatty. It is synthesized in the endoplasmic reticulum by ceramide synthase.

Biochem./physiol. Wirkung

Ceramide functions as a secondary messenger to initiate apoptosis. It also regulates physiological processes and is accountable for the epidermal permeability barrier in eukaryotic membranes.

Verpackung

2 mL Amber Glass Sealed Ampule (LM2212-1EA)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

FlameExclamation mark
GHS02,GHS07

Signalwort

Danger

H-Sätze

H225,H319

Gefahreneinstufungen

Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 1

Flammpunkt (°F)

55.4 °F - closed cup

Flammpunkt (°C)

13.0 °C - closed cup

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Mammalian Ceramide Synthases
Levy M and Futerman AH
Febs Letters, 62(5), 347-356 (2010)
The enigma of ceramide synthase regulation in mammalian cells
Wegner MS, et al.
Progress in Lipid Research, 63, 93-119 (2016)
Nesli-Ece Sen et al.
International journal of molecular sciences, 20(23) (2019-11-27)
Ataxin-2 (human gene symbol ATXN2) acts during stress responses, modulating mRNA translation and nutrient metabolism. Ataxin-2 knockout mice exhibit progressive obesity, dyslipidemia, and insulin resistance. Conversely, the progressive ATXN2 gain of function due to the fact of polyglutamine (polyQ) expansions
Radiation and ceramide-induced apoptosis
Kolesnick R and Fuks Z
Oncogene, 22(37), 5897-5897 (2003)
Guang-Yi Dai et al.
The Journal of biological chemistry, 295(3), 717-728 (2019-12-11)
Cellular membranes contain many lipids, some of which, such as sphingolipids, have important structural and signaling functions. The common sphingolipid glucosylceramide (GlcCer) is present in plants, fungi, and animals. As a major plant sphingolipid, GlcCer is involved in the formation

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