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880135P

Avanti

DSPE-PEG(2000) Carboxylic Acid

Avanti Research - A Croda Brand 880135P, powder

Synonym(e):

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt)

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Empirische Formel (Hill-System):
C131H257NNaO55P
CAS-Nummer:
Molekulargewicht:
2780.38
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

powder

Verpackung

pkg of 1 × 10 mg (880135P-10mg)
pkg of 1 × 100 mg (880135P-100mg)
pkg of 1 × 25 mg (880135P-25mg)
pkg of 1 × 50 mg (880135P-50mg)
pkg of 1 × 500 mg (880135P-500mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 880135P

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

[H][C@@](COP([O-])(OCCNC(C/C=C\OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOCCOOCC(O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=

Allgemeine Beschreibung

Carboxylic acids are readily soluble in polar solvents such as water and alcohols. DSPE-PEG(2000) carboxylic acid consists of a hydrophilic polyethylene glycol (PEG) chain of 2kDa.

Anwendung

DSPE-PEG(2000) carboxylic acid has been used:
  • to covalently conjugate integrin α-2 (ITGA2) antibodies to the surface of the liposomes
  • in the preparation of atosiban-conjugated liposomes
  • to prepare dual complementary liposome

Biochem./physiol. Wirkung

DSPE-PEG(2000) carboxylic acid increases the blood circulation time of liposomes. The carboxyl group of DSPE-PEG(2000) carboxylic acid aids in covalent conjugation with antibodies.

Verpackung

20 mL Clear Glass Screw Cap Vial (880135P-500mg)
5 mL Amber Glass Screw Cap Vial (880135P-100mg)
5 mL Amber Glass Screw Cap Vial (880135P-10mg)
5 mL Amber Glass Screw Cap Vial (880135P-25mg)
5 mL Amber Glass Screw Cap Vial (880135P-50mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

auch häufig zusammen mit diesem Produkt gekauft

Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

No data available

Flammpunkt (°C)

No data available


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Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Dual complementary liposomes inhibit triple-negative breast tumor progression and metastasis
Guo P, et al.
Science advances, 5(3), eaav5010-eaav5010 (2019)
Carboxylic Acid: Key Role in Life Sciences (2019)
ITGA2 as a potential nanotherapeutic target for glioblastoma
Guo P, et al.
Scientific reports, 9(1), 6195-6195 (2019)
Feifei Yang et al.
Small (Weinheim an der Bergstrasse, Germany), 16(7), e1906360-e1906360 (2020-01-24)
Hepatotoxicity is a key concern in the clinical translation of nanotherapeutics because preclinical studies have consistently shown that nanotherapeutics accumulates extensively in the liver. However, clinical-stage nanotherapeutics have not shown increased hepatotoxicity. Factors that can contribute to the hepatotoxicity of
Anujan Ramesh et al.
Nanoscale, 12(3), 1875-1885 (2020-01-07)
Tumor associated macrophages (TAMs) play an important role in initiating the immunosuppressive environment that negatively impacts the immunotherapy efficacy and has long been linked with cancer progression. On the other hand, activated macrophages display immense phagocytic potential and can be

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