860498P

Sphinganine (d18:0)

Avanti Research^™ - A Croda Brand

• Synonym(e): D-erythro-sphinganine
• Empirische Formel (Hill-System): C₁₈H₃₉NO₂
• CAS-Nummer: 764-22-7
• Molekulargewicht: 301.51
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Form: powder
• Verpackung: pkg of 1 × 10 mg (860498P-10mg); pkg of 1 × 100 mg (860498P-100mg); pkg of 1 × 25 mg (860498P-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand
• Lipid-Typ: sphingolipids
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: OC[C@@](N)([H])[C@]([H])(O)CCCCCCCCCCCCCCC
• InChI: 1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/m0/s1
• InChIKey: OTKJDMGTUTTYMP-ZWKOTPCHSA-N

Beschreibung

Allgemeine Beschreibung

Sphinganine (d18:0) is a substrate for the enzyme ceramide desaturase. It is synthesized indirectly due to the interconversion of supplemented glycine to serine. Sphinganine (d18:0) is catabolized to ceramide.

Anwendung

Sphinganine (d18:0) has been used:

• as a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramides
• as a medium supplement to test its effect on growth of yeast cells
• in the preparation of bovine serum albumin lipid complex to investigate its effect on non-lysosomal - glucosylceramidase β2 (GBA2) inhibition

Biochem./physiol. Wirkung

Sphinganine (d18:0) levels are not altered in hereditary sensory neuropathy type 1 cells. Accumulation of d18:0 is observed in tumor hypoxia. It is useful as a biomarker for studying microbial diversity.

Verpackung

5 mL Amber Glass Screw Cap Vial (860498P-100mg)

5 mL Amber Glass Screw Cap Vial (860498P-10mg)

5 mL Amber Glass Screw Cap Vial (860498P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable