840513P

18:1 Phosphatidylethanol

1,2-dioleoyl-sn-glycero-3-phosphoethanol (sodium salt), powder

• Synonym(e): 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanol (sodium salt)
• Empirische Formel (Hill-System): C₄₁H₇₆O₈PNa
• CAS-Nummer: 322647-53-0
• Molekulargewicht: 751.00
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Verpackung: pkg of 1 × 25 mg (840513P-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 840513P
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@@](COP([O-])(OCC)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C41H77O8P.Na/c1-4-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(42)46-37-39(38-48-50(44,45)47-6-3)49-41(43)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-5-2;/h19-22,39H,4-18,23-38H2,1-3H3,(H,44,45);/q;+1/p-1/b21-19-,22-20-;/t39-;/m1./s1
• InChIKey: AHVVHDCFEFPKMN-AOEFFCPUSA-M

Beschreibung

Allgemeine Beschreibung

18:1 Phosphatidylethanol (PEth)/1,2-dioleoyl-sn-glycero-3-phosphoethanol is a sodium salt of modified lipid, wherein C-1, C-2 of glycerol is substituted with 9Z-octadecenolyl and C-3 of glycerol is substituted by phosphoethanol group. This lipid metabolite of ethanol has two oleic acid chains.

Anwendung

18:1 Phosphatidylethanol (PEth)/1,2-dioleoyl-sn-glycero-3-phosphoethanol may be used:

• as a standard in liquid chromatography−mass spectrometry (LC-MS) analysis of PEth in human whole blood
• as a reference material in quantifying phosphatidylethanol in human blood by liquid chromatography high resolution mass spectrometry (LC−HRMS )
• to incorporate into human high density lipoprotein (HDL) particles to study its effects on the secretion of vascular endothelial growth factor (VEGF) in cultured human smooth muscle cells

Biochem./physiol. Wirkung

Phosphatidylethanol (PEth) obtained from phosphatidylcholine in erythrocytes can acts as an important biomarker for alcohol consumption.

Verpackung

5 mL Clear Glass Sealed Ampule (840513P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids