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810226P

Avanti

C6-NBD Lactosyl Ceramide

Avanti Research™ - A Croda Brand 810226P, powder

Synonym(e):

N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-D-lactosyl-β1-1′-sphingosine

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About This Item

Empirische Formel (Hill-System):
C42H69N5O16
CAS-Nummer:
474943-04-9
Molekulargewicht:
900.02
UNSPSC-Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 1 mg (810226P-1MG)
pkg of 1 × 250 μg (810226P-250ug)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 810226P

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

C6-NBD Lactosyl ceramide is a commercially available fluorescent analog of compound lactosyl ceramide. Lactosyl ceramide is present on neutrophils and macrophages.

Anwendung

C6-NBD Lactosyl Ceramide has been used in:
  • lactosylceramide synthase assay as a fluorescent acceptor substrate identified using fluorescence based detector in HPLC(1)
  • phospholipid labeling and fluorescence-lifetime imaging microscopy (FILM) of cell membranes(6)

Biochem./physiol. Wirkung

Lactosyl ceramide is utilized for synthesis of various glycosphingolipids like oligoglycosylceramides and gangliosides in vertebrates. It is an important molecule involved in signaling cascades leading to phenotypic changes such as adhesion, migration, cell proliferation and angiogenesis.

Verpackung

5 mL Amber Glass Screw Cap Vial (810226P-1MG)
5 mL Amber Glass Screw Cap Vial (810226P-250ug)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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W I Weis et al.
Annual review of biochemistry, 65, 441-473 (1996-01-01)
Lectins are responsible for cell surface sugar recognition in bacteria, animals, and plants. Examples include bacterial toxins; animal receptors that mediate cell-cell interactions, uptake of glycoconjugates, and pathogen neutralization; and plant toxins and mitogens. The structural basis for selective sugar
S Hakomori et al.
Journal of biochemistry, 118(6), 1091-1103 (1995-12-01)
Glycosphingolipids (GSLs), cell type-specific markers which change dramatically during ontogenesis and oncogenesis, have been implicated as playing major roles in cellular interactions and control of cell proliferation in multicellular organisms. These functional roles have been partially clarified through two types

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