700149P
Avanti
16:0 cholesteryl-d7 ester
Avanti Research™ - A Croda Brand 700149P, powder
Synonym(e):
cholesteryl-d7 palmitate
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About This Item
Empirische Formel (Hill-System):
C43H69D7O2
CAS-Nummer:
Molekulargewicht:
632.11
UNSPSC-Code:
41141804
NACRES:
NA.25
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Assay
>99% (TLC)
Form
powder
Verpackung
pkg of 1 × 10 mg (700149P-10mg)
pkg of 1 × 25 mg (700149P-25mg)
Hersteller/Markenname
Avanti Research™ - A Croda Brand 700149P
Versandbedingung
dry ice
Lagertemp.
−20°C
Allgemeine Beschreibung
Cholesteryl palmitate is a cholesteryl ester. 16:0 cholesteryl-d7 ester is the deuterated form of cholesteryl palmitate or 16:0 cholesteryl ester.
Anwendung
16:0 cholesteryl-d7 ester has been used:
- in plasma sample preparation for tandem mass spectrometry analysis (MS/MS)
- as an internal standard in mass spectrometry for quantification of nerve lipids from mice
- as an internal standard in time-of-flight mass spectrometry (TOFMS) for the quantification of serum extracellular vesicles (EVs) lipids
- as an external calibrator and internal spiking standard in tandem mass spectroscopy measurements
- in liposome preparation for retinyl ester hydrolase (REH) and cholesteryl esterase activity assay
Biochem./physiol. Wirkung
Cholesteryl palmitate is associated with atherosclerotic plaque. Deuterated cholesteryl palmitate in used in reconstituting high-density lipoprotein (HDL). An elevated levels of the ratio of cholesteryl oleate to cholesteryl palmitate is implicated with apoptotic cell death in the atherosclerotic lesions.
Verpackung
5 mL Amber Glass Screw Cap Vial (700149P-10mg)
5 mL Amber Glass Screw Cap Vial (700149P-25mg)
Rechtliche Hinweise
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Beschreibung
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Lagerklassenschlüssel
11 - Combustible Solids
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Suming Chen et al.
Journal of circulating biomarkers, 8, 1849454419879848-1849454419879848 (2019-10-22)
There is a wide variety of extracellular vesicles (EVs) that differ in size and cargo composition. EVs isolated from human plasma or serum carry lipid, protein, and RNA cargo that provides insights to the regulation of normal physiological processes, and
Mithilesh Kumar Jha et al.
Glia, 68(1), 161-177 (2019-08-28)
Schwann cell (SC)-specific monocarboxylate transporter 1 (MCT1) knockout mice were generated by mating MCT1 f/f mice with myelin protein zero (P0)-Cre mice. P0-Cre+/- , MCT1 f/f mice have no detectable early developmental defects, but develop hypomyelination and reduced conduction velocity
Matias M Vazquez et al.
Redox biology, 36, 101591-101591 (2020-06-13)
Macrophages play a pivotal role in the early stages of atherosclerosis development; they excessively accumulate cholesterol in the cytosol in response to modified Low Density Lipoprotein (mLDL). The mLDL are incorporated through scavenger receptors. CD36 is a high-affinity cell surface
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