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H31859
5-Hydroxy-indol
97%
Synonym(e):
5-Indolol, 5-Hydroxy-indol
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About This Item
Empirische Formel (Hill-System):
C8H7NO
CAS-Nummer:
Molekulargewicht:
133.15
Beilstein:
112349
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
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Qualitätsniveau
Assay
97%
mp (Schmelzpunkt)
106-108 °C (lit.)
SMILES String
Oc1ccc2[nH]ccc2c1
InChI
1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
InChIKey
LMIQERWZRIFWNZ-UHFFFAOYSA-N
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Verwandte Kategorien
Anwendung
- Reactant for preparation of (oxoimidazolidinyl/oxopyrimidinyl)benzenesulfonates as antitumor agents and tubulin inhibitors
- Reactant for preparation of anthranilic acids
- Reactant for preparation of indole compounds as dopamine D2 receptor antagonists
- Reactant for preparation of naphthalimide- or carbazole-containing human β-adrenoceptor ligands
- Reactant for preparation of melanins as nature-inspired radioprotectors
- Reactant for preparation of 5-vinyl-3-pyridinecarbonitriles as PKCθ inhibitors
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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Xiang-Qun Hu et al.
Neuropharmacology, 54(8), 1153-1165 (2008-04-26)
Allosteric modulation of ligand-gated ion channels can play important roles in shaping synaptic transmission. The function of the 5-hydroxytryptamine (serotonin) type 3 (5-HT(3)) receptor, a member of the Cys-loop ligand-gated ion channel superfamily, is modulated by a variety of compounds
Ruth Livingstone et al.
The Journal of chemical physics, 135(19), 194307-194307 (2011-11-25)
Time-resolved photoelectron spectroscopy was used to obtain new information about the dynamics of electronic relaxation in gas-phase indole and 5-hydroxyindole following UV excitation with femtosecond laser pulses centred at 249 nm and 273 nm. Our analysis of the data was
Eva-Maria Karg et al.
Journal of medicinal chemistry, 52(11), 3474-3483 (2009-06-06)
Pharmacological suppression of leukotriene biosynthesis by inhibitors of 5-lipoxygenase (5-LO) is a strategy to intervene with inflammatory and allergic disorders. We recently presented 2-amino-5-hydroxy-1H-indoles as efficient 5-LO inhibitors in cell-based and cell-free assays. Structural optimization led to novel benzo[g]indole-3-carboxylates exemplified
Gretchen Y López-Hernández et al.
Neuropharmacology, 56(4), 821-830 (2009-08-26)
One approach for the identification of therapeutic agents for Alzheimer's disease has focused on the research of alpha7 nAChR-selective agonists such as the partial agonists 3-(4-hydroxy,2-methoxybenzylidene)anabaseine (4OH-GTS-21) and, more recently, 2-[2-(4-bromophenyl)-2-oxoethyl]-1-methyl pyridinium (S 24795). An alternative approach for targeting alpha7
Yu-Bo Wu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(20-21), 1847-1855 (2009-06-02)
To make analytes amenable for fluorescence (FL) detection, polymer monolith microextraction (PMME) coupled to high-performance liquid chromatography with FL detection was developed for the simultaneous determination of catechols and 5-hydroxyindoleamines (5-HIAs) from urine samples. In this method, a two-step pre-column
Global Trade Item Number
| SKU | GTIN |
|---|---|
| H31859-250MG | |
| H31859-50G | |
| H31859-1G | 4061833792858 |
| H31859-250G | |
| H31859-25G | |
| H31859-500MG |
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