G10105

18β-Glycyrrhetinsäure

97%

• Synonym(e): Enoxolon, Glycyrrhetin, Subglycyrrhelinsäure, Uralensäure
• Empirische Formel (Hill-System): C₃₀H₄₆O₄
• CAS-Nummer: 471-53-4
• Molekulargewicht: 470.68
• Beilstein: 2229654
• EG-Nummer: 207-444-6
• MDL-Nummer: MFCD00003706
• UNSPSC-Code: 12352115
• PubChem Substanz-ID: 24895033
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Optische Aktivität: [α]22/D +170.0°, c = 1 in chloroform
• mp (Schmelzpunkt): 292-295 °C (lit.)
• SMILES String: CC1(C)[C@@H](O)CC[C@@]2(C)[C@H]1CC[C@]3(C)[C@@H]2C(=O)C=C4[C@@H]5C[C@](C)(CC[C@]5(C)CC[C@@]34C)C(O)=O
• InChI: 1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,22-,23+,26+,27-,28-,29+,30+/m0/s1
• InChIKey: MPDGHEJMBKOTSU-YKLVYJNSSA-N
• Angaben zum Gen: human ... HSD11B1(3290) , HSD11B2(3291) ; rat ... Hsd11b1(25116) , Hsd11b2(25117)

Beschreibung

Allgemeine Beschreibung

18β-Glycyrrhetinic acid is a pentacyclic triterpenoid found in the Glycyrrhiza glabra L.(liquorice) roots. It is the key metabolite of glycyrrhizin and glycyrrhizic acid.

Anwendung

The product may be used as a starting material to prepare 18β-glycyrrhetinic acid derivatives, which show anti-inflammatory and antioxidant properties.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves