E33505

Isonipecotat-Ethyl

98%

• Synonym(e): Ethyl-piperidin-4-carboxylat
• Empirische Formel (Hill-System): C₈H₁₅NO₂
• CAS-Nummer: 1126-09-6
• Molekulargewicht: 157.21
• Beilstein: 118419
• EG-Nummer: 214-416-7
• MDL-Nummer: MFCD00006003
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24894508
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 98%
• Form: liquid
• Brechungsindex: n20/D 1.459 (lit.)
• bp: 204 °C (lit.)
• Dichte: 1.02 g/mL at 25 °C (lit.)
• SMILES String: CCOC(=O)C1CCNCC1
• InChI: 1S/C8H15NO2/c1-2-11-8(10)7-3-5-9-6-4-7/h7,9H,2-6H2,1H3
• InChIKey: RUJPPJYDHHAEEK-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for synthesis of:

• SMN protein modulators
• β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition
• Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone
• RhoA inhibitors for cardiovascular disease therapy
• Saccharin derived Mannich bases as antimicrobials and antioxidants

Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 176.0 °F - closed cup
• Flammpunkt (°C): 80 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)