931845

GenOx-PJ

• Synonym(e): 3-Oxo-2-tosyl-2,3-dihydro-1H-1λ₃-benzo[d][1,2]iodazol-1-yl acetate
• Empirische Formel (Hill-System): C₁₆H₁₄INO₅S
• CAS-Nummer: 2243393-44-2
• Molekulargewicht: 459.26
• UNSPSC-Code: 12352200
• NACRES: NA.21

Eigenschaften

• Form: powder
• Qualitätsniveau: 100
• mp (Schmelzpunkt): >300 °C
• Funktionelle Gruppe: iodo
• Lagertemp.: −20°C

Beschreibung

Anwendung

GenOx-PJ is an iodine(III) based oxidant developed by Genentech as part of a robust method of forming C-O bonds through direct coupling of carboxylic acids with alcohols. When used with a Ru(II) photocatalyst, GenOx-PJ is active in the decarboxylative coupling of a broad range of carboxylic acids--including primary, secondary, tertiary, as well as peptides--with alcohols. By this method, GenOx-PJ enables a direct approach in utilizing simple, readily available substrates to perform this type of coupling, and providing many synthetic applications.

Sonstige Hinweise

A Platform for Decarboxylative Couplings via Photoredox Catalysis: Direct Access to Carbocations from Carboxylic Acids for Carbon−Oxygen Bond Formation

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable