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702153

Sigma-Aldrich

Hydroxylapatit

nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)

Synonym(e):

Calcium hydroxide phosphate, Calcium hydroxylapatite, Calcium hydroxyphosphate, Nano hydroxyapatatite, Pentacalcium hydroxide triphosphate

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About This Item

Lineare Formel:
[Ca5(OH)(PO4)3]x
CAS-Nummer:
12167-74-7
Molekulargewicht:
502.31
MDL-Nummer:
MFCD00010904
UNSPSC-Code:
12352302
PubChem Substanz-ID:
329762350
NACRES:
NA.23

Form

dispersion
nanoparticles

Qualitätsniveau

100

Enthält

≤0.025 wt. % dispersant (non-metal based)

Konzentration

10 wt. % in H2O

Oberflächenbereich

14.3 m2/g , typical

Partikelgröße

<200 nm (BET)

pH-Wert

4-6

Dichte

1.038 g/mL at 25 °C

SMILES String

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChIKey

XYJRXVWERLGGKC-UHFFFAOYSA-D

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Allgemeine Beschreibung

Hydroxyapatite(HAP) is an osteoconductive bioceramic material which has uniqueability to form direct bonds with living tissues. It can be easily prepared byvarious techniques such as sol-gel, hydrothermal, multiple emulsion, biomimeticdeposition, and electrodeposition.

Anwendung

Hydroxyapatite can be used as:
  • An implant material for bone substitute due to its chemical similarity to the inorganic component of bone and osteo inductive properties.
  • A vehicle for gene and drug delivery because of its encapsulation capacity and affinity to several drugs and proteins.
  • A pH responsive particulate emulsifier.

Leistungsmerkmale und Vorteile

  • Biocompatible
  • Osteoconductive
  • Stable under physiological conditions
  • High mechanical strength

Rechtliche Hinweise

Product of Engi-Mat Co.

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
MKCP8250
MKCN6392
MKCL6094
MKBW5896V
MKBR8934V

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Die Dokumentenbibliothek aufrufen

Liam M Grover et al.
Biomaterials, 34(28), 6631-6637 (2013-06-12)
Pyrophosphate ions are both inhibitors of HA formation and substrates for phosphatase enzymes. Unlike polyphosphates their hydrolysis results simultaneously in the complete loss of mineral formation inhibition and a localised elevation in orthophosphate ion concentration. Despite recent advances in our
W Zhang et al.
Journal of dental research, 92(12), 1136-1141 (2013-10-08)
Stem cell-based bone tissue engineering has been recognized as a new strategy for maxillary sinus floor elevation. More rapid bone formation may enhance this technique when simultaneous dental implant placement is desired. Adipose tissue-derived stem cells (ADSCs) and bone marrow
Satyavrata Samavedi et al.
Acta biomaterialia, 9(9), 8037-8045 (2013-06-25)
Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the regeneration of bone tissue because of their ability to induce osteoblastic differentiation in progenitor cells. Despite the progress made towards fabricating CPCs possessing a range of surface features
Xi Chen et al.
The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)
Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly
Thomas Lyon et al.
The Journal of bone and joint surgery. American volume, 95(23), 2088-2096 (2013-12-07)
Recombinant human bone morphogenetic protein-2 (rhBMP-2) applied on an absorbable collagen sponge improves open tibial fracture-healing as an adjunct to unreamed intramedullary nail fixation. We evaluated rhBMP-2 and a new, injectable calcium phosphate matrix (CPM) formulation in acute closed tibial
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