670774
(R)-(−)-Pyrrolidin-3-Carboxylsäure
≥99.0% (NT)
Synonym(e):
(R)-β-Prolin
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Alle Fotos(2)
About This Item
Empfohlene Produkte
Assay
≥99.0% (NT)
Form
solid
Optische Aktivität
[α]/D -20.5±1.5°, c = 2 in H2O
Eignung der Reaktion
reaction type: solution phase peptide synthesis
Anwendung(en)
peptide synthesis
Lagertemp.
2-8°C
SMILES String
OC(=O)[C@@H]1CCNC1
InChI
1S/C5H9NO2/c7-5(8)4-1-2-6-3-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1
InChIKey
JAEIBKXSIXOLOL-SCSAIBSYSA-N
Verpackung
Bottomless glass bottle. Contents are inside inserted fused cone.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Journal of the American Chemical Society, 130(3), 875-886 (2008-01-01)
The development of enantioselective anti-selective Mannich-type reactions of aldehydes and ketones with imines catalyzed by 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives is reported in detail. Both (3R,5R)-5-methyl-3-pyrrolidinecarboxylic acid and (R)-3-pyrrolidinecarboxylic acid efficiently catalyzed the reactions of aldehydes with alpha-imino esters
The Journal of organic chemistry, 70(19), 7634-7639 (2005-09-10)
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The Journal of organic chemistry, 77(23), 10925-10930 (2012-11-07)
A straightforward stereoselective and enantiodivergent cyclization strategy for the construction of γ-lactams is described. The cyclization strategy makes use of chiral malonic esters prepared from enantiomerically enriched monoesters of disubstituted malonic acid. The cyclization occurs with the selective displacement of
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