515213

Methyl-3-indolglyoxylat

98%

• Synonym(e): Methyl 2-(indol-3-yl)-2-oxoacetate
• Empirische Formel (Hill-System): C₁₁H₉NO₃
• CAS-Nummer: 18372-22-0
• Molekulargewicht: 203.19
• MDL-Nummer: MFCD00047173
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24873805
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• mp (Schmelzpunkt): 227-230 °C (lit.)
• Funktionelle Gruppe: ester; ketone
• SMILES String: COC(=O)C(=O)c1c[nH]c2ccccc12
• InChI: 1S/C11H9NO3/c1-15-11(14)10(13)8-6-12-9-5-3-2-4-7(8)9/h2-6,12H,1H3
• InChIKey: VFIJGAWYVXDYLK-UHFFFAOYSA-N

Beschreibung

Anwendung

• Reactant for preparation of sotrastaurin analogs as protein kinase inhibitors
• Reactant for synthesis of GSK-3 inhibitors
• Reactant for Diels-Alder cycloaddition
• Reactant for preparation of a Janus kinase 3 inhibitor
• Reactant for synthesis of cephalandole alkaloids
• Reactant for stereoselective preparation of COX-2 inhibitor as anticancer agent
• Reactant for synthesis of cycloalkene indole carbazole alkaloids via ring-closing metathesis

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves