460516

Ethyl-(R)-(+)-4-chlor-3-hydroxybutyrat

96%

• Lineare Formel: ClCH₂CH(OH)CH₂CO₂C₂H₅
• CAS-Nummer: 90866-33-4
• Molekulargewicht: 166.60
• MDL-Nummer: MFCD00211242
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 24869705
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 96%
• Optische Aktivität: [α]23/D +14°, neat
• Optische Reinheit: ee: 97% (GLC)
• Brechungsindex: n20/D 1.453 (lit.)
• bp: 93-95 °C/5 mmHg (lit.)
• Dichte: 1.19 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro; ester; hydroxyl
• SMILES String: CCOC(=O)C[C@@H](O)CCl
• InChI: 1S/C6H11ClO3/c1-2-10-6(9)3-5(8)4-7/h5,8H,2-4H2,1H3/t5-/m1/s1
• InChIKey: ZAJNMXDBJKCCAT-RXMQYKEDSA-N

Beschreibung

Anwendung

Ethyl (R)-(+)-4-chloro-3-hydroxybutyrate is a chiral building block that can be used:

• To prepare allyl stannane, a precursor for the total synthesis of macrolide iriomoteolide-1b.
• As a starting material for the synthesis of a chiral g-αmino acid fragment, which in turn is used to prepare the immunosuppressive agent FR252921.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H318
• P-Sätze: P280 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Dam. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter