441287

(1S)-(+)-2-Azabicyclo[2.2.1]hept-5-en-3-on

≥98%

• Empirische Formel (Hill-System): C₆H₇NO
• CAS-Nummer: 130931-83-8
• Molekulargewicht: 109.13
• MDL-Nummer: MFCD00211275
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24867650
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98%
• Optische Aktivität: [α]20/D +565°, c = 1 in chloroform
• Optische Reinheit: ee: 99% (HPLC)
• mp (Schmelzpunkt): 94-97 °C (lit.)
• SMILES String: O=C1N[C@H]2C[C@@H]1C=C2
• InChI: 1S/C6H7NO/c8-6-4-1-2-5(3-4)7-6/h1-2,4-5H,3H2,(H,7,8)/t4-,5+/m0/s1
• InChIKey: DDUFYKNOXPZZIW-CRCLSJGQSA-N

Beschreibung

Anwendung

This lactam and its antipode are precursors to the enantiomers of the carbocyclic nucleoside carbovir. It has been demonstrated that (-)-carbovir is a potent inhibitor of HIV-1 and based on clinical trials it could become an alternative to AZT. AZT is a trademark of The Wellcome Foundation Ltd.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315 - H319 - H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves