438626
4-Hydroxy-3-nitrocumarin
98%
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
Empirische Formel (Hill-System):
C9H5NO5
CAS-Nummer:
Molekulargewicht:
207.14
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
Empfohlene Produkte
Qualitätsniveau
Assay
98%
mp (Schmelzpunkt)
172 °C (dec.) (lit.)
Funktionelle Gruppe
ester
ketone
nitro
SMILES String
OC1=C(C(=O)Oc2ccccc12)[N+]([O-])=O
InChI
1S/C9H5NO5/c11-8-5-3-1-2-4-6(5)15-9(12)7(8)10(13)14/h1-4,11H
InChIKey
NZQAQAUWFHMVEM-UHFFFAOYSA-N
Allgemeine Beschreibung
4-Hydroxy-3-nitrocoumarin is a coumarin derivative and its cytotoxic action against cultured human tumor and normal cells has been investigated. It can be prepared by the nitration of 4-hydroxycoumarin in glacial acetic acid by using 72% HNO3.
Anwendung
4-Hydroxy-3-nitrocoumarin may be used as starting reagent for the synthesis of following compounds:
- 4-chloro-3-nitrocoumarin
- 2-unsubstituted 3-nitrochromone
- 4-amino-3-nitrocoumarins
Signalwort
Danger
H-Sätze
Gefahreneinstufungen
Acute Tox. 3 Oral
Lagerklassenschlüssel
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Biljana R Dekić et al.
Molecules (Basel, Switzerland), 15(4), 2246-2256 (2010-04-30)
Synthesis, spectral analysis and bioactivity of new coumarin derivatives are described in this paper. Eight new coumarin derivatives were synthesized in moderate to good yields by condensation of 4-chloro-3-nitrocoumarin and the corresponding heteroarylamine. The synthesized compounds were tested for their
Masami Kawase et al.
In vivo (Athens, Greece), 19(4), 705-711 (2005-07-08)
A preliminary exploration of coumarin derivatives as novel multidrug resistance (MDR) modulators was carried out to determine the basic features of the structure responsible for the MDR reversal activity. Among 44 coumarins, 14 compounds moderately induced the reversal of MDR
Vidoslav Dekić et al.
Magnetic resonance in chemistry : MRC, 48(11), 896-902 (2010-09-08)
Herein, we describe the synthesis and complete assignment of the (1)H and (13)C NMR chemical shifts of a series of antimicrobial 4-arylamino-3-nitrocoumarin derivatives based on a combination of (1)H and (13)C NMR, (1)H-(1)H-COSY, NOESY, HSQC and HMBC experiments. Conformational effects
Synthesis of heteroannulated 3-nitro-and 3-aminopyridines by cyclocondensation of electron-rich aminoheterocycles with 3-nitrochromone.
Iaroshenko VO, et al.
Tetrahedron, 68(11), 2532-2543 (2012)
Investigations of pyrans and related compounds.
Savel'ev VL, et al.
Chemistry of Heterocyclic Compounds, 9(7), 816-820 (1973)
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
Setzen Sie sich mit dem technischen Dienst in Verbindung.