419362

Di-tert-butyl-N,N-diisopropylphosphoramidit

95%

• Synonym(e): Di-tert-butyl diisopropylphosphoramidite
• Lineare Formel: [(CH₃)₂CH]₂NP[OC(CH₃)₃]₂
• CAS-Nummer: 137348-86-8
• Molekulargewicht: 277.38
• Beilstein: 4858847
• MDL-Nummer: MFCD00153506
• UNSPSC-Code: 12352001
• PubChem Substanz-ID: 24866105
• NACRES: NA.22

Eigenschaften

• Assay: 95%
• Form: liquid
• Eignung der Reaktion: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• Brechungsindex: n20/D 1.444 (lit.)
• bp: 85-90 °C/0.2 mmHg (lit.)
• Dichte: 0.879 g/mL at 25 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: CC(C)N(C(C)C)P(OC(C)(C)C)OC(C)(C)C
• InChI: 1S/C14H32NO2P/c1-11(2)15(12(3)4)18(16-13(5,6)7)17-14(8,9)10/h11-12H,1-10H3
• InChIKey: YGFLCNPXEPDANQ-UHFFFAOYSA-N

Beschreibung

Anwendung

Di-tert-butyl N,N-diisopropylphosphoramidite is a general reagent to introduce tert-butyl-protected phosphate groups. It is commonly used in phosphorylation of biomolecules. It can also be used in the synthesis of phosphoramidate-linked glycoconjugates.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter