418951

(DHQD)₂Pyr

97%

• Synonym(e): Hydrochinidin-(2,5-diphenyl-4,6-pyrimidindiyl)-diether
• Empirische Formel (Hill-System): C₅₆H₆₀N₆O₄
• CAS-Nummer: 149725-81-5
• Molekulargewicht: 881.11
• MDL-Nummer: MFCD00198108
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24866252
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Optische Aktivität: [α]20/D −390°, c = 1.2 in methanol
• mp (Schmelzpunkt): 247-250 °C (lit.)
• SMILES String: CC[C@H]1CN2CCC1CC2[C@@H](Oc3nc(nc(O[C@H](C4CC5CCN4C[C@@H]5CC)c6ccnc7ccc(OC)cc67)c3-c8ccccc8)-c9ccccc9)c%10ccnc%11ccc(OC)cc%10%11
• InChI: 1S/C56H60N6O4/c1-5-35-33-61-27-23-39(35)29-49(61)52(43-21-25-57-47-19-17-41(63-3)31-45(43)47)65-55-51(37-13-9-7-10-14-37)56(60-54(59-55)38-15-11-8-12-16-38)66-53(50-30-40-24-28-62(50)34-36(40)6-2)44-22-26-58-48-20-18-42(64-4)32-46(44)48/h7-22,25-26,31-32,35-36,39-40,49-50,52-53H,5-6,23-24,27-30,33-34H2,1-4H3/t35-,36-,39-,40-,49+,50+,52-,53-/m0/s1
• InChIKey: SWKRDCRSJPRVNF-DOGDSVMGSA-N

Beschreibung

Anwendung

(DHQD)₂Pyr may be used:

• To catalyze the enantioselective allylic amination of alkylidene cyanoacetates with dialkyl azodicarboxylates.
• To prepare 10(R),11-Dihydroxydihydroquinine and 10(S),11-dihydroxydihydroquinine via the Sharpless catalytic asymmetric dihydroxylation.
• In the total synthesis of okadaic acid, a protein phosphatase inhibitor.

Rechtliche Hinweise

Sold under license from Rhodia Pharma Solutions.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves