391263

2-Dimethylaminoethanol

purified by redistillation, ≥99.5%

• Synonym(e): N,N-Dimethyl-2-hydroxyethylamin, N,N-Dimethylethanolamin
• Lineare Formel: (CH₃)₂NCH₂CH₂OH
• CAS-Nummer: 108-01-0
• Molekulargewicht: 89.14
• Beilstein: 1209235
• EG-Nummer: 203-542-8
• MDL-Nummer: MFCD00002846
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24864369
• NACRES: NA.22

Eigenschaften

• Dampfdruck: 100 mmHg ( 55 °C); 6.12 mmHg ( 20 °C)
• Qualitätsniveau: 100
• Assay: ≥99.5%
• Form: liquid
• Aufgereinigt durch: redistillation
• Brechungsindex: n20/D 1.4294 (lit.)
• bp: 134-136 °C (lit.)
• mp (Schmelzpunkt): −70 °C (lit.)
• Löslichkeit: alcohol: miscible(lit.); water: soluble
• Dichte: 0.886 g/mL at 20 °C (lit.)
• Funktionelle Gruppe: amine; hydroxyl
• SMILES String: CN(C)CCO
• InChI: 1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3
• InChIKey: UEEJHVSXFDXPFK-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-Dimethylaminoethanol (DMAE/deanol) is an amino alcohol. It is the main product formed during the amination of ethylene glycol by dimethylamine on alumina supported copper in a continuous fixed-bed reactor. DMAE has been reported to be the putative precursor of acetylcholine. Its effect as a skin-firming and anti-wrinkle agent has been studied. Microwave spectrum of 2-dimethylaminoethanol has been investigated. Its effect as an organic additive on deposition and anti-reflective properties of porous CaF₂ has been studied. Removal of the benzyl ester groups by transesterification with 2-dimethylaminoethanol from benzyl protected tripeptides has been reported.

Anwendung

2-Dimethylaminoethanol (deanol) may be used as a ligand in the copper-catalyzed amination of aryl bromides and iodides.
2-Dimethylaminoethanol (deanol, DMAE, DMEA) may be used in the synthesis of the following:

• cis -[Co(sac)₂(dmea)₂] and cis -[Zn(sac)₂(dmea)₂] (sac=saccharinate)
• heterotrinuclear complex [Cu₂Zn(NH₃)I₃(Me₂Ea)₃ (HMe₂Ea=2-dimethylaminoethanol)
• 2-alkoxy-N,N-dimethylethylamine
• mixed-metal complexes of copper(II) and lead(II)

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS05
• Signalwort: Danger
• H-Sätze: H226,H302 + H312,H314,H331,H335
• P-Sätze: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 104.0 °F - Seta closed cup
• Flammpunkt (°C): 40 °C - Seta closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter