376876

N-Methoxy-N-methyl(triphenylphosphoranyliden)acetamid

98%

• Synonym(e): (N-Methoxymethylaminocarbonylmethylen)-triphenylphosphoran
• Lineare Formel: (C₆H₅)₃P=CHCON(OCH₃)CH₃
• CAS-Nummer: 129986-67-0
• Molekulargewicht: 363.39
• Beilstein: 4198472
• MDL-Nummer: MFCD00134433
• UNSPSC-Code: 12352002
• PubChem Substanz-ID: 24863472
• NACRES: NA.22

Eigenschaften

• Assay: 98%
• Eignung der Reaktion: reaction type: C-C Bond Formation
• mp (Schmelzpunkt): 173-175 °C (lit.)
• Funktionelle Gruppe: amine; phosphine
• SMILES String: CON(C)C(=O)C=P(c1ccccc1)(c2ccccc2)c3ccccc3
• InChI: 1S/C22H22NO2P/c1-23(25-2)22(24)18-26(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,1-2H3
• InChIKey: DGBLSOOPDBHHRX-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for:

• Synthesis of electron-deficient alkenes via stereoselective olefination of N-sulfonyl imines
• Phosphine-catalyzed asymmetric addition reactions
• Cysteine-catalyzed enantioselective intramolecular Rauhut-Currier reaction
• Wittig olefination
• Synthesis of aigialomycin D, a Protein Kinase inhibitor and a potential anticancer agent

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves