369675

(S)-(+)-α-Methoxy-α-trifluormethylphenylacetyl-chlorid

99%

• Synonym(e): (S)-(+)-MTPA-Cl, Moshers Säurechlorid
• Lineare Formel: C₆H₅C(OCH₃)(CF₃)COCl
• CAS-Nummer: 20445-33-4
• Molekulargewicht: 252.62
• Beilstein: 3591562
• MDL-Nummer: MFCD00067105
• UNSPSC-Code: 12352101
• PubChem Substanz-ID: 24863007
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 99%
• Form: liquid
• Optische Reinheit: ee: 98% (GLC)
• Brechungsindex: n20/D 1.469 (lit.)
• bp: 213-214 °C (lit.)
• Dichte: 1.35 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: acyl chloride; ether; fluoro; phenyl
• Lagertemp.: −20°C
• SMILES String: CO[C@@](C(Cl)=O)(c1ccccc1)C(F)(F)F
• InChI: 1S/C10H8ClF3O2/c1-16-9(8(11)15,10(12,13)14)7-5-3-2-4-6-7/h2-6H,1H3/t9-/m1/s1
• InChIKey: PAORVUMOXXAMPL-SECBINFHSA-N

Beschreibung

Allgemeine Beschreibung

(S)-(+)-α-Methoxy-α-trifluoromethylphenylacetyl chloride is commonly used as a derivatizing agent in Mosher ester analysis and Mosher amide analysis, which are NMR-based methods for determining the absolute configuration of the chiral carbon center in secondary alcohols and amines, respectively.

Anwendung

Used in the synthesis of natural products and pheromones.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

doi:10.1038/nprot.2007.354

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Gefahreneinstufungen: Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 192.2 °F - closed cup
• Flammpunkt (°C): 89 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter