343609

(R)-(+)-Methyl-p-tolylsulfoxid

99%

• Synonym(e): (+)-(R)-Methyl 4-tolyl sulfoxide, (+)-Methyl p-tolyl sulfoxide, (R)-4-Methylphenyl methyl sulfoxide, 1-Methyl-4-[(R)-methylsulfinyl]benzene
• Lineare Formel: CH₃C₆H₄S(O)CH₃
• CAS-Nummer: 1519-39-7
• Molekulargewicht: 154.23
• Beilstein: 2040677
• MDL-Nummer: MFCD00151502
• UNSPSC-Code: 12191600
• PubChem Substanz-ID: 24861180
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Optische Aktivität: [α]20/D +145°, c = 2 in acetone
• Optische Reinheit: ee: 99% (HPLC)
• mp (Schmelzpunkt): 73-75 °C (lit.)
• Funktionelle Gruppe: sulfoxide
• SMILES String: Cc1ccc(cc1)S(C)=O
• InChI: 1S/C8H10OS/c1-7-3-5-8(6-4-7)10(2)9/h3-6H,1-2H3/t10-/m1/s1
• InChIKey: FEVALTJSQBFLEU-SNVBAGLBSA-N

Beschreibung

Allgemeine Beschreibung

(R)-(+)-Methyl p-tolyl sulfoxide may be used to prepare (R)-(+)-methyl 3,5-dimethoxy-6-[8-oxo-9-(p-tolylsulfinyl) nonyl] benzoate, an intermediate for (R)-lasiodiplodin synthesis. Its anions undergo addition reaction with nitrones to form optically active a-substituted N-hydroxylamines. (R)-(+)-Methyl p-tolyl sulfoxide also reacts with O-mesitylsulfonylhydroxylamine (MSH) to form (-)-(R)-S-methyl-S-p-tolylsulfoximine.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)