269107

L-tert.-Leucin

99%, for peptide synthesis

• Synonym(e): (S)-2-Amino-3,3-dimethyl-buttersäure, L-α-tert.-Butylglycin
• Lineare Formel: (CH₃)₃CCH(NH₂)CO₂H
• CAS-Nummer: 20859-02-3
• Molekulargewicht: 131.17
• Beilstein: 1721824
• MDL-Nummer: MFCD00064218
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 24856311
• NACRES: NA.22

Eigenschaften

• Produktbezeichnung: L-tert.-Leucin, 99%
• Qualitätsniveau: 200
• Assay: 99%
• Form: powder
• Optische Aktivität: [α]20/D −9.5°, c = 3 in H₂O
• Optische Reinheit: ee: 99% (GLC)
• Eignung der Reaktion: reaction type: solution phase peptide synthesis
• mp (Schmelzpunkt): ≥300 °C (lit.)
• Anwendung(en): peptide synthesis
• SMILES String: CC(C)(C)[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-6(2,3)4(7)5(8)9/h4H,7H2,1-3H3,(H,8,9)/t4-/m1/s1
• InChIKey: NPDBDJFLKKQMCM-SCSAIBSYSA-N

Beschreibung

Allgemeine Beschreibung

L-tert-Leucine is an amino acid used as a precursor for synthesizing chiral tridentate Schiff base ligands.

Anwendung

L-tert-Leucine can be used:

• As a key precursor in the synthesis of a chiral phosphinooxazoline ligand, (S)-tert-butylPHOX.
• In the synthesis of chiral copper(II) polymers that can catalyze the kinetic resolution of secondary alcohols by acylation.
• In metal-free tandem radical cyclization reactions to synthesize 6-alkyl/acyl phenanthridines.
• In the preparation of tert-leucine-derived N-acetylthiazolidinethione auxiliary that provides high levels of diastereoselection in acetate aldol reactions with a variety of aldehydes.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)