240230
Phthalimid
≥99%
Synonym(e):
1,3-Dihydro-1,3-dioxoisoindol
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Alle Fotos(4)
About This Item
Empfohlene Produkte
Assay
≥99%
mp (Schmelzpunkt)
232-235 °C (lit.)
Löslichkeit
water: slightly soluble(lit.)
SMILES String
O=C1NC(=O)c2ccccc12
InChI
1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-4H,(H,9,10,11)
InChIKey
XKJCHHZQLQNZHY-UHFFFAOYSA-N
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Anwendung
Phthalimide was used in the synthesis of 6-amino agarose (AA) by Mitsunobu-inspired microwave mediated method.
Lagerklassenschlüssel
13 - Non Combustible Solids
WGK
WGK 1
Flammpunkt (°F)
302.0 °F - closed cup
Flammpunkt (°C)
150 °C - closed cup
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Carbohydrate polymers, 106, 365-373 (2014-04-12)
A facile 6-aminoagarose (AA) mediated synthesis of new fluorogenic amides of agarose with nicotinic (AA-NA) and picolinic acids (AA-PA) employing carbodiimide chemistry have been described. 6-Amino agarose (AA) was synthesized in a facile Mitsunobu-inspired microwave mediated method involving the reaction
Journal of veterinary science, 21(5), e60-e60 (2020-10-06)
Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. The aim of the study was to assess the pharmacokinetics of
Organic letters, 10(6), 1179-1182 (2008-02-23)
A novel palladium-catalyzed intermolecular aminopalladation/C-H activation method for selectively synthesizing (E)-(2-oxindolin-3-ylidene)phthalimides has been developed. In the presence of Pd(OAc)2 and PhI(OAc)2, alkynes were difunctionalized with a phthalimide and an arene sp2 C-H bond to selectively synthesize (E)-(2-oxoindolin-3-ylidene)phthalimides, which products are
Journal of the American Chemical Society, 131(27), 9473-9474 (2009-07-09)
A new method for the synthesis of beta(3)-amino acids is presented. Phthalimide protected allylic amines are oxidized under Wacker conditions selectively to aldehydes using PdCl(2) and CuCl or Pd(MeCN)(2)Cl(NO(2)) and CuCl(2) as complementary catalyst systems. The aldehydes are produced in
Journal of medicinal chemistry, 52(23), 7432-7445 (2009-09-08)
We have discovered two related chemical series of nonpeptide urotensin-II (U-II) receptor antagonists based on piperazino-phthalimide (5 and 6) and piperazino-isoindolinone (7) scaffolds. These structure types are distinctive from those of U-II receptor antagonist series reported in the literature. Antagonist
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