233161

3′-(Trifluormethyl)acetophenon

99%

• Synonym(e): 3-Acetyl-benzotrifluorid
• Lineare Formel: CF₃C₆H₄COCH₃
• CAS-Nummer: 349-76-8
• Molekulargewicht: 188.15
• Beilstein: 640151
• EG-Nummer: 206-490-4
• MDL-Nummer: MFCD00000391
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24853957
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Form: liquid
• Brechungsindex: n20/D 1.4611 (lit.)
• bp: 198-200 °C (lit.)
• Dichte: 1.235 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: fluoro; ketone
• SMILES String: CC(=O)c1cccc(c1)C(F)(F)F
• InChI: 1S/C9H7F3O/c1-6(13)7-3-2-4-8(5-7)9(10,11)12/h2-5H,1H3
• InChIKey: ABXGMGUHGLQMAW-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Asymmetric catalytic addition of ethyl groups to 3′-(trifluoromethyl)acetophenone catalyzed by ligands derived from trans-1,2-diaminocyclohexane and camphor sulfonyl chloride has been reported. Phenylation of 3′-(trifluoromethyl)acetophenone in the presence of dihydroxy bis(sulfonamide) ligand (enantioselective catalyst), titanium tetraisopropoxide and diphenylzinc has been investigated.

Anwendung

3′-(Trifluoromethyl)acetophenone has been used in a key step during the preparation of a commercial fungicide.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): 174.2 °F - closed cup
• Flammpunkt (°C): 79 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter