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Merck

200689

Sigma-Aldrich

Ethylcellulose

viscosity 10 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl

Synonym(e):

ethylcellulose

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12162002
NACRES:
NA.23

Form

powder

Selbstzündungstemp.

698 °F

Kennzeichnungsgrad

48% ethoxyl

Brechungsindex

n20/D 1.47 (lit.)

Viskosität

10 cP, 5 % in toluene/ethanol 80:20(lit.)

Übergangstemp.

softening point 155 °C

Dichte

1.14 g/mL at 25 °C (lit.)

SMILES String

O1[C@H](C(C(C(C1COCC)OCC)OCC)OCC)O[C@@H]2C(OC(C(C2OCC)OCC)OCC)COCC

InChIKey

MINRZDZESGXKDM-OLIDUAMRSA-N

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Allgemeine Beschreibung

Ethyl cellulose(EC) is a hydrophobic andphysiologically inert cellulose derivative. It is widely used to preparephysiological dosage forms. It can also be used as a polymer coating,particle emulsion stabilizer and in pharmaceuticallyuseful aqueous latex dispersions.

Anwendung

Ethyl cellulose can be used as a starting material to prepare zein-based nanofibers for controlled drug release. The addition of EC improves the solubility and mechanical properties of the composite nanofibers.

It can be used to prepare graphene-based ink for inkjet printing. This graphene oxide ink printed onto ITO surfaces can be used as an electrode for label-free DNA sensing.

Owing to its unique features such as gastroresistance, biocompatibility, and degradation to non-toxic and readily excreted products, EC is widely used in oral and topical drug dosage forms for the controlled release of the drug.

Leistungsmerkmale und Vorteile

  • Non-toxic
  • Stable
  • Compressible

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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N Suwannateep et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(3), 485-490 (2012-09-08)
The phytochemical curcumin possesses antioxidant activity; however, it becomes unstable after being exposed to light or heat or loses activity during storage. This is especially important when curcumin is applied to the skin within a cosmetic or pharmaceutical formulation, since
Syed Umer Jan et al.
Pakistan journal of pharmaceutical sciences, 25(4), 751-756 (2012-09-27)
The aim and objective of the present study was to formulate and evaluate controlled release polymeric tablets of ibuprofen with determinations of formulation factors using various grades and types of polymer ethocel i.e. ethocel standard 10P; 10FP, 100P and100FP for
Daniela Traini et al.
International journal of pharmaceutics, 438(1-2), 150-159 (2012-09-12)
The potential of excipient coating to enhance aerosol performance of micronized drugs in carrier excipient-drug blends, used in dry powder inhalers, was investigated. Both EC (ethyl cellulose) and PVP (polyvinylpyrrolidone) were used as coating agents. Carriers were prepared via sieve
Ghulam Murtaza
Acta poloniae pharmaceutica, 69(1), 11-22 (2012-05-12)
Ethylcellulose (EC) based microencapsulated drug delivery systems are being extensively studied throughout the world for achieving extended drug release and protecting the core substance from degradation. The in vitro evaluation of EC microcapsules have elucidated that their particle characteristics are
Ritesh M Pabari et al.
Expert opinion on drug delivery, 9(12), 1463-1474 (2012-10-16)
To examine the potential of a novel 3-fluid nozzle spray drying technology to formulate differentiated layered microparticles (MPs) of diclofenac sodium (DFS)/ethyl cellulose (EC). DFS/EC MPs were formulated using the inner and/or outer nozzles of a novel 3-fluid nozzle and

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