194905

12-Krone-4

98%

• Synonym(e): 1,4,7,10-Tetraoxacyclododecan
• Empirische Formel (Hill-System): C₈H₁₆O₄
• CAS-Nummer: 294-93-9
• Molekulargewicht: 176.21
• Beilstein: 1363064
• EG-Nummer: 206-036-5
• MDL-Nummer: MFCD00005103
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24851661
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Form: liquid
• Brechungsindex: n20/D 1.463 (lit.)
• bp: 61-70 °C/0.5 mmHg (lit.)
• mp (Schmelzpunkt): 16 °C (lit.)
• Dichte: 1.089 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: ether
• SMILES String: C1COCCOCCOCCO1
• InChI: 1S/C8H16O4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h1-8H2
• InChIKey: XQQZRZQVBFHBHL-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

12-Crown-4 is a crown ether generally used as a ligand in coordination chemistry. It is also known as lithium ionophore because of its strong chelating property specific to lithium cation.

Anwendung

12-Crown-4 can be used as:

• A promoter in the synthesis of poly(diethylsiloxane) (PDES) from monomer hexaethylcyclotrisiloxane using NaOH as a catalyst via anionic ring-opening polymerization.
• As an additive in the preparation of triarylmethane derivatives by palladium-catalyzed cross coupling reaction of aryl bromides with diarylmethane derivatives.
• A phase transfer catalyst in organic synthesis.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H330
• P-Sätze: P260 - P271 - P284 - P304 + P340 + P310 - P403 + P233 - P405
• Gefahreneinstufungen: Acute Tox. 1 Inhalation
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 235.4 °F - closed cup
• Flammpunkt (°C): 113 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter