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Merck

185507

Sigma-Aldrich

2-Naphthol

99%

Synonym(e):

β-Naphthol, 2-Hydroxynaphthalin

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About This Item

Lineare Formel:
C10H7OH
CAS-Nummer:
Molekulargewicht:
144.17
Beilstein:
742134
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
eCl@ss:
39023410
PubChem Substanz-ID:
NACRES:
NA.22

Dampfdichte

4.97 (vs air)

Qualitätsniveau

Dampfdruck

10 mmHg ( 145.5 °C)

Assay

99%

Form

powder or flakes

bp

285-286 °C (lit.)

mp (Schmelzpunkt)

120-122 °C (lit.)

Löslichkeit

methanol: soluble 1 g/10 mL, clear, colorless to light yellow

SMILES String

Oc1ccc2ccccc2c1

InChI

1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H

InChIKey

JWAZRIHNYRIHIV-UHFFFAOYSA-N

Angaben zum Gen

human ... CYP1A2(1544)

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Allgemeine Beschreibung

2-Naphthol undergoes three-component one-pot condensation reaction with ureas/amides and aldehydes catalyzed by sulfamic acid under ultrasound irradiation to give 1-amidoalkyl-2-naphthols. Anodic oxidation of 2-naphthol in acidic media has been investigated at a synthetic boron-doped diamond thin film electrode using cyclic voltammetry and bulk electrolysis.

Anwendung

<ul>
<li><strong>Transformation Reactions in Organic Chemistry:</strong> It is also involved in recent advances in the transformation reactions of Betti base derivatives during the synthesis of 1-(alpha;-aminobenzyl)-2-naphthol (Olyaei and Sadeghpour, 2024).</li>
</ul>

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

307.4 °F - closed cup

Flammpunkt (°C)

153 °C - closed cup

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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A three-component one-pot condensation of 2-naphthol, ureas/amides and aldehydes catalyzed by sulfamic acid, under ultrasound irradiation and ambient conditions gives 1-amidoalkyl-2-naphthols in excellent yield and in short time.
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