158631

4′-Chloracetanilid

97%

• Synonym(e): N-(4-Chlorphenyl)-acetamid, Essigsäure-4-chlor-anilid, NSC 40563, NSC 444
• Lineare Formel: CH₃CONHC₆H₄Cl
• CAS-Nummer: 539-03-7
• Molekulargewicht: 169.61
• Beilstein: 509638
• EG-Nummer: 208-707-8
• MDL-Nummer: MFCD00000612
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24849769
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Form: solid
• mp (Schmelzpunkt): 176-178 °C (lit.)
• Funktionelle Gruppe: amide
• SMILES String: CC(=O)Nc1ccc(Cl)cc1
• InChI: 1S/C8H8ClNO/c1-6(11)10-8-4-2-7(9)3-5-8/h2-5H,1H3,(H,10,11)
• InChIKey: GGUOCFNAWIODMF-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

4′-Chloroacetanilide is the main impurity present in acetaminophen and has been quantitated by new high-performance liquid chromatography method using a mixed-mode reversed-phase/cation exchange stationary phase.

Anwendung

<ul>
<li><strong>High-performance liquid chromatography (HPLC) method validation:</strong> 4 chloroacetanilide is used as an internal standard for isosorbide dinitrate in the assay of sustained-release tablets or capsules containing nitroglycerin, isosorbide dinitrate, or pentaerythritol tetranitrate by high-performance liquid chromatography (Gelber and Papas, 1983).</li>
</ul>

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves