103764

Pentafluorbenzolsulfonylchlorid

99%

• Synonym(e): 2,3,4,5,6-Pentafluorophenylsulfonyl chloride, Perfluorobenzenesulfonyl chloride
• Lineare Formel: C₆F₅SO₂Cl
• CAS-Nummer: 832-53-1
• Molekulargewicht: 266.57
• Beilstein: 2142325
• EG-Nummer: 212-620-0
• MDL-Nummer: MFCD00007427
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24846621
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 99%
• Form: solid
• Brechungsindex: n20/D 1.479 (lit.)
• bp: 210-211 °C (lit.)
• Dichte: 1.796 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro; fluoro
• SMILES String: Fc1c(F)c(F)c(c(F)c1F)S(Cl)(=O)=O
• InChI: 1S/C6ClF5O2S/c7-15(13,14)6-4(11)2(9)1(8)3(10)5(6)12
• InChIKey: UOJCTEGNHXRPKO-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Pentafluorobenzenesulfonyl chloride reacts with benzene and thiophene derivatives in the presence of a ruthenium (II) catalyst to form corresponding perfluorophenylated compounds.

Anwendung

Pentafluorobenzenesulfonyl chloride was used as derivatizing reagent for simultaneous determination of fluoxetine and p-trifluoromethylphenol, an O-dealkylated metabolite of fluoxetine in human liver microsomes. Pentafluorobenzenesulfonyl chloride was used for electrophore labeling of small tyrosyl peptides for their analysis by gas chromatography with electron-capture detection.

Biochem./physiol. Wirkung

Pentafluorobenzenesulfonyl chloride is derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detectio.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 194.0 °F - closed cup
• Flammpunkt (°C): 90 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges