TYK2
tyrosine kinase 2
Synonyme:
JTK1
Spezies:
Human TYK2 (7297), Mouse Tyk2 (54721), Rat Tyk2 (100361294), Zebrafish tyk2 (100536675), chicken TYK2 (430113), dog TYK2 (476714), domestic cat TYK2 (101090171), cow TYK2 (512484), sheep TYK2 (101117248), domestic guinea pig Tyk2 (100715734)
UniProtKB-ID:
Gen-ID:
- Human(7297) Summary: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
- Mouse(54721) tyrosine kinase 2
- Rat(100361294) tyrosine kinase 2
- Zebrafish(100536675) tyrosine kinase 2
- chicken(430113) tyrosine kinase 2
- dog(476714) tyrosine kinase 2
- domestic cat(101090171) tyrosine kinase 2
- cow(512484) tyrosine kinase 2
- sheep(101117248) tyrosine kinase 2
- domestic guinea pig(100715734) tyrosine kinase 2
- naked mole-rat(101715782) tyrosine kinase 2
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ELISA
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Antibodies
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Speziesreaktivität
Anwendung
Anti-TYK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TYK2 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse
Anwendung
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-TYK2 Antibody, clone 2H22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
bovine, human, monkey, porcine
Anwendung
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-TYK2 antibody produced in mouse, clone 6G12, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-phospho-TYK2 (pTyr1054) antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot
Small Molecule - Inhibitor
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esiRNA
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