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Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

Synonyme:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit

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Antibodies

Product Number
Beschreibung
Speziesreaktivität
Anwendung
Anti-SCN8A Sodium Channel Antibody, Chemicon®, from rabbit,
Speziesreaktivität
mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

western blot
Anti-SCN8A, affinity isolated antibody,
Speziesreaktivität
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Anwendung
western blot
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-SCN8A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence

Small Molecule - Blocker

Product Number
Beschreibung
Spezies
Lidocainhydrochlorid, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Lidocain -hydrochlorid Monohydrat, solid,
Spezies
human
Procain -hydrochlorid, ≥97%,
Spezies
human
Lidocain, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Procainamid -hydrochlorid, ≥98% (HPLC),
Spezies
human

esiRNA

Product Number
Beschreibung
Spezies
MISSION® esiRNA, targeting mouse Scn8a,
Spezies
mouse