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Merck

RYK

receptor-like tyrosine kinase

Synonyme:
D3S3195, JTK5, JTK5A, RYK1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(6259) Summary: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]
  • Mouse(20187) receptor-like tyrosine kinase
  • Rat(140585) receptor-like tyrosine kinase
  • Zebrafish(558502) receptor-like tyrosine kinase
  • chicken(395409) receptor-like tyrosine kinase
  • domestic cat(101086838) receptor-like tyrosine kinase
  • dog(477074) receptor-like tyrosine kinase
  • cow(781353) receptor-like tyrosine kinase
  • sheep(101114583) receptor-like tyrosine kinase
  • domestic guinea pig(100727608) receptor-like tyrosine kinase
  • naked mole-rat(101722098) receptor-like tyrosine kinase
  • Domestic Rabbit(100008628) receptor-like tyrosine kinase

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ELISA

Produktnummer
Beschreibung
Spezies
Phosphotyrosine RYK ELISA Kit, ,
Spezies
human
Human Ryk ELISA, for serum, plasma and cell culture supernatants,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-RYK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-RYK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
Anti-RYK antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunohistochemistry

western blot
Anti-RYK (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry

western blot

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human RYK,
Spezies
human
MISSION® esiRNA, targeting mouse Ryk,
Spezies
mouse